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Dr. Hakonarson is director of the Center for Applied Genomics and professor of Pediatrics at the Perelman School of Medicine, University of Pennsylvania. He leads a $40 million commitment from Children’s Hospital of Philadelphia to genomically characterize approximately 100,000 children, an initiative that has gained nationwide attention in the Wall Street Journal, New York Times, Time Magazine, Nature, and Science.
Dr. Hamilton studies intestinal epithelial cells and how they help maintain human health. Although there is a great deal understood about how these cells function, little is known about how they behave during disease. Dr. Hamilton focuses on defining new mechanisms in regenerative medicine, inflammatory bowel disease, and colorectal cancer.
Dr. Heuckeroth investigates mechanisms controlling bowel motility in order to find new ways to treat, diagnose, and prevent intestinal motility disorders. He works to define genetic, biochemical, and cellular processes that impact bowel function, with a special interest in the enteric nervous system and intestinal smooth muscle cells.
Dr. Hill seeks to understand how the immune system contributes to the two most common chronic diseases of childhood: allergy and obesity. He uses clinical and epidemiological information to guide basic and translational research on the genetic, epigenetic, and immunologic basis of these important conditions.
Dr. Hill’s research interests include identifying strategies to help parents, children, and healthcare providers cope with stressful situations; coping skills in the context of serious illness; how parents develop new goals when a child’s health is declining; good parent beliefs of parents of seriously ill children; and changes in self-concept for parents caring for a child with a life-threatening illness.
Developing and implementing strategy to lead the operations of the research-related regulatory, compliance, and safety programs across all types of research including human, animal, and laboratory-based research.
Dr. Huang works on methodology development to understand the dynamics of disease activities and inform health management using multivariate longitudinal health data. She also works on data integration in Clinical Research Networks.