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Dr. De Leon-Crutchlow’s translational research program focuses on examining the pathophysiology of disorders of insulin regulation, identifying novel therapeutic targets, and developing new therapies for these conditions. The program approach includes patient-oriented research and bench research employing mouse models and primary islet cultures.
Dr. Doupnik’s research investigates how to ensure that children can access effective mental health services. She uses methods from diverse fields, including epidemiology, comparative effectiveness, and health policy research. Currently, she is focused on suicide prevention and integration of mental health services into children’s hospitals.
The research interests of Dr. Downes focus on antimicrobial clinical pharmacology and pharmacoepidemiology in children with a goal to identify novel approaches to optimize efficacy, minimize toxicity, and limit antimicrobial resistance from antibiotics.