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Amanda M. Ackermann, MD, PhD

Amanda M. Ackermann

Dr. Ackermann studies diabetes (types 1 and 2) and congenital hyperinsulinism using mouse models, cell lines, and primary human tissue. She aims to identify novel pathways regulating beta cell insulin secretion, leading to innovative therapeutic strategies for these disorders. Current studies include in vivo mouse physiology, ex vivo human islet physiology, CRISPR-Cas9 gene editing, epigenetic modification, and single-cell functional genomics.


Denise Adams, MD

Denise Adams

Dr. Adams is director of the Comprehensive Vascular Anomalies Program, a cutting-edge, multidisciplinary program that seeks breakthrough treatments and cures for children, adolescents, and young adults with rare, life-threatening tumors and malformations of the vasculature.


N. Scott Adzick, MD, MMM, FACS, FAAP

N. Scott Adzick

The founder and director of CHOP's Center for Fetal Diagnosis and Treatment, Dr. Adzick is an innovator in the field of fetal medicine, pursuing groundbreaking prenatal treatment for debilitating birth defects. He led the NIH-funded "Management of Myelomeningocele Study" (MOMS) at CHOP, a breakthrough research program that showed fetal surgery for spina bifida results in significantly improved outcomes.


Rebecca C. Ahrens-Nicklas, MD, PhD

Rebecca C. Ahrens-Nicklas, MD, PhD

Dr. Ahrens-Nicklas works to understand why patients with inherited biochemical disorders often suffer severe, untreatable neurologic and cardiac symptoms. She strives to elucidate the link between biochemistry and network excitability, in order to drive new approaches to therapy.


Julian L. Allen, MD

Julian L. Allen

The research interests of Dr. Allen include lung function testing in children, adolescents, and infants; developmental chest wall physiology; pulmonary complications of sickle cell disease; and complications of cystic fibrosis.


Stewart A. Anderson, MD

Stewart A. Anderson

Dr. Anderson’s research interests focus on the molecular and cellular mechanisms that govern the development of the mammalian forebrain. In his research on the development of the cerebral cortex, he is particularly interested in understanding the molecular underpinnings behind the fate determination and axon targeting of subclasses of GABAergic interneurons implicated in the neuropathology of schizophrenia.


Yair Argon, PhD

Yair Argon

Dr. Argon investigates the unfolded protein response (UPR) , an essential signaling network that determines life or death of stressed cells and tissues. The IRE1 sensor of UPR responds to metabolic stress through four distinct activities and he focuses on determining which stress condition induces each activity and how they are integrated to enable the cells to cope with stress.


Alexandre Arkader, MD

Alexandre Arkader

Dr. Arkader is one of few orthopedic surgeons in the country with formal training in both pediatric orthopedics and orthopedic oncology. He has a special interest in complex trauma and limb deformities, and specializes in external fixation methods and other minimally invasive techniques for limb preservation and equalization benefiting growing children.


Valder R. Arruda, MD, PhD

Valder R. Arruda

The development of gene-based strategies for the treatment of bleeding and thrombotic diseases is at the heart of research by Dr. Arruda. Working collaboratively, Dr. Arruda and his colleagues have carried out early-phase clinical studies on adeno-associated viral vectors for the treatment of severe hemophilia B.