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Dr. O'Connor investigates the immunological aspects of heart transplantation in children, specifically the impact of anti-HLA antibodies. The presence of these antibodies can complicate or even prevent a transplant from happening; therefore, reducing or eliminating them before transplant is important for a patient to receive a heart that is compatible with his or her immune system.
Dr. O'Byrne is a pediatric cardiologist with research interests in cardiac disease outcomes, perioperative outcomes, and children with pulmonary hypertension. He combines the use of large observational datasets to study outcomes, practice variation, cost, and the determinants of health-related quality of life in this population.