Find Research Studies | CHOP Research Institute

Find Research Studies | CHOP Research Institute

1 - 246 of 246

16BT052; Unrelated And Partially Matched Related Donor PSCT w/ TCR αβ depletion for patients with BMF

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A Study to Evaluate the Safety andEfficacy of a Single Dose of CTX001 in Subjects With Severe Sickle Cell Disease

AA Genetic Study

AALL1131; A Phase 3 Randomized Trial for HR B-ALL with Dasatinib Arm in Ph-like TKI Sensitive Mutations

AALL1521; Ruxolitinib and Chemotherapy for Patients with JAK-Mutant B-ALL

AAML1921; Bosutinib for Chronic Myeloid Leukemia

Abatacept Registry

Abemaciclib For Solid Tumors

ADHD ETA Driving Cohort Study

Adolescent Communication of Emotion Study (ACES)

Allo CD7 CAR WU-CART-007

Alpelisib in PIK3CA-related overgrowth syndrome

ALRN-6924 in Pediatric Cancer

Alterra Adaptive Clinical Trial

ANBL1232 Response & Biology Risk Factors in Patients with Non-High-Risk Neuroblastoma

Aneurysms in ARPKD

ARPKD/HRFD Database

Astellas Clinical Trial for ASP0367

Autism ETA Cohort Study

Autism Quality of Life

B

BA3011 for advanced solid tumors

Beta-cell Responsiveness to the Incretin Hormones (Aim1)

Blood Sugar Stability in Individuals with Hyperinsulinism

BMT CTN 1503 (STRIDE2): BMT for SCD

Bone Marrow Failure Research Study and Repository

BPD STAR Pilot Trial

Brain and Behavior Learning Health System Biorepository

C

Canagliflozin in Children with Type 2 Diabetes

Cancer Genomic Testing Study

Carfilzomib in ALL

CATC Biorepository

CBTTC Collection Protocol

CD33xCD3 Bispecific Antibody in AML

CFRD-Pilot Study

Chemotherapy-induced Nausea and Vomiting Control

Chronic Incretin-based therapy in Cystic Fibrosis (Aim 2)

Coaching and Asynchronous Remote Training for Evidence-Based Practices (CARE)

Comorbidity of Autism and Epilepsy

Contrast-Enhanced Ultrasound Evaluation of Bowel Perfusion in Necrotizing Enterocolitis

Contrast-Enhanced Ultrasound Evaluation of Hypoxic Ischemic Injury

Copanlisib in Solid Tumors or Lymphoma

CP-SMC Pilot Study

Craniofacial Pathologies

CrCEST MRI in Mitochondrial Disease

CTX and Idiopathic Bilateral Cataracts in Pediatric Patients

D

Daratumumab for T-cell ALL

Dasiglucagon for the Treatment of Children with Congenital Hyperinsulinism

Dasiglucagon for the Treatment of Children with Congenital Hyperinsulinism (for children under 1 year of age)

DCA Trial in PDC Deficiency

Defining Clinically Meaningful Outcome Measures For Children With Axial Juvenile Spondyloarthritis

Designing the ThyTSQ for Teens and Parents

Disease Flare in sJIA

Distracted Driving App Study

Dova Study for Children with Immune Thrombocytopenia (ITP)

Drive Focus Study

Driving After Concussion in Adolescents

DTX401 Gene Therapy in Glycogen Storage Disease (GSD) Type Ia

E

EDIT-301: Phase 1/2 Sickle Cell Disease Gene Therapy Trial

Elamipretide for Adult Patients with Primary Mitochondrial Disease

Emergence and Progression of AGT

Endotheliopathy in Oncology

Ertugliflozin for Children and Adolescents with Type 2 Diabetes

Evaluation of Diffuse Amplified Musculoskeletal Pain Syndrome Using MEG

Executive Function and Healthcare Transition in IMD

F

Facial Nerve Paralysis Database

FLG Mutations and Atopic Dermatitis

Flo Prospective Trials

Floreo Focus Groups

Fontan Liver MRE

Food Allergy Anxiety

Friedreich Ataxia Clinical Outcomes Measures

FVRx + Home Plate

G

Gene Therapy Trial for Hemophilia A

Gladiolus Study

Gluten-Free Diet Adherence in Children with Celiac Disease

H

Head Start 4 Protocol for Children with Medulloblastoma and CNS Embryronal Tumors

Health Disparities in Pediatric Sleep

Healthy Children Needed for Single Study Visit on Immunometabolic Dysregulation

Healthy Controls EndoPAT

HGB-212: Phase 3 Beta Thalassemia LentiGlobin BB305 Gene Therapy Trial

HM15136 for the Treatment of Congenital Hyperinsulinism Research Study

Hodgkin Lymphoma (NHL) (BIANCA)

HR-pQCT Pilot Study

HRpQCT in Childhood Osteoporosis

Humanized CART19 Phase 2 Trial

I

ILAR Reclassification Study

Imaging Assessment of Bone Sarcomas

Imaging Cognition and Neurodevelopment (ICAN)

Infant-Caregiver Synchrony in Autism

Inflammatory Bowel Disease and Yoga

Intranasal Oxytocin in Hypothalamic Obesity

J

Juvenile SpA Repository

K

L

Larsen Syndrome: Risk factors for Thoracic Insufficiency Syndrome

Leftover Surgical Specimen Collection Study (Brain Tumor Focus)

Leigh Syndrome Natural History Study

LeukoSEQ: First-Line Whole Genome Sequencing in Leukodystrophies

Lifespan Brain Institute Common Screening and Intake Protocol

Literacy Focus Group

Locomotor Learning- Infant MEG

Longitudinal ABP And Atherosclerosis In PSLE

Lurbinectedin in Ewing Sarcoma

Lutathera in Somatostatin Neuroendocrine Tumors

M

Managing Feeding and Sleep at Home

MEG Biomarkers in Autistic Adults

Melatonin, Sleep, and Mental Health

Metabolic MRI: Pilot Testing

Microbiome, Antibiotics and Growth Infant Cohort (MAGIC) Study

Mitochondrial Myopathy Rating Scale

MRI of ARPKD liver disease

MRI Study for Infants with Down Syndrome

MRI Study for Prediction of ASD

N

National Pediatric Cardiology Quality Improvement Collaborative

Natural History of Homocystinuria

Natural History of PMM2-Congenital Disorder of Glycosylation

Neoneur Feeding System

NEPENTHE - Next Generation Personalized Neuroblastoma Therapy

Neuroscience Biorepository

NICU RISE (Rotavirus Immunization Safety Evaluation)

Non-Invasively Assessing Lung Ventilation in Pediatrics

Novel Imaging Techniques in Autosomal Recessive Polycystic Kidney Disease

O

Omics Study For CDG Patient

Online Mindfulness Course for Pediatric IBD

Optimizing Vancomycin Therapy in Children

P

Palbociclib, Irinotecan, and Temozolomide in Ewing Sarcoma

PANDA Study – Mobile App

Partnering to Achieve School Success (PASS) Study

PBKR03 for Krabbe Disease

PBS for Renal Tumors

Pediatric KIDney Stone (PKIDS) Care Improvement Network

Pediatric Mito MRI Study

Pediatric Neurodegenerative Biorepository

Pediatric Normative Data for the Complete Minnesota Dexterity Test

Pediatric Research Immune Network on SARS-CoV-2 and MIS-C (PRISM)

Pediatric Study of Acute Recurrent and Chronic Pancreatitis

PERCEPTION Study

Phase 1 Study Of Lentivirally Transduced T Cells Engineered To Contain Anti-CD123 In Subjects With Refractory Or Relapsed Acute Myeloid Leukemia

Phase 1 Trial of CUDC-907

Phase 2 trial of CART19 for Orphan Indications Of Pediatric B Cell Acute Lymphoblastic Leukemia (B-ALL)

Phase 3 Beta Thalassemia LentiGlobin BB305 Gene Therapy Trial

Phase II Mayo Clinic Stem Cell Trial for HLHS

Phenotypes of Congenital Hyperinsulinism

Phenotyping Congenital Hyperinsulinism

Polyethylene Glycol Safety in Children

Preventing Distracted Driving

Prevention of Urinary Stones with Hydration

Prodigy huCART19

Progression of SMA

Project RISE (Resources and Internal Supports for Evidence-based Practices)

PRONTO-PEDS: Ultra-Rapid Insulin Lispro in T1D

Providing Unique Support for Health (PUSH)

PTEN Hamartoma Tumor Syndrome Phenotyping

R

Ramucirumab for Desmoplastic Small Round Cell Tumor (DSRCT)

Ramucirumab for Recurrent/Refractory Synovial Sarcoma

REN001 for Adults with Primary Mitochondrial Myopathy

Repotrectinib for ALK, ROS1, or NTRK1-3 Alterations

Research Study for Individuals with Hyperinsulinism, Type 1 Diabetes Mellitus, and Healthy Children

Research Study for Individuals with Hyperinsulinism/Hyperammonemia

Research Study for Patients with GSD III

Reverse Transcriptase Inhibitors in Aicardi Goutieres Syndrome

RGX-111 Gene Therapy in Patients With Mucopolysaccharidosis Type I (MPS I)

RGX-121 Gene Therapy in Patients With MPS II (Hunter Syndrome)

Ribociclib With Everolimus And Dexamethasone For Relapsed ALL

RIZE Clinical Trial for Individuals with Hyperinsulinism

RM-493-034: Setmelanotide in MC4R Study

S

Safety and Efficacy of Early-Start Deferiprone Treatment in Infants and Young Children Newly Diagnosed with Transfusion-Dependent Beta Thalassemia

Safety and Efficacy of NB-001 in 22q11DS Children with Anxiety, Inattention, and/or Autism

Sangamo Gene Therapy for Thalassemia (ST-400-01)

SECURE-AIC Registry

Seeking Healthy Participants for Muscle Accrual Study

Selpercatinib in Solid or CNS tumors with RET-Alterations

Sex, Gender, and Camouflage in ASD

Shifting Perspectives

Skeletal and Dental Quality in Adolescents with Urinary Stone Disease

Skeletal Growth Study

Sleep and Growth Study 2

Sleep Apnea in People with Beckwith-Wiedemann Syndrome

Sleep Questionnaire for Infants with or at high-risk of Cerebral Palsy

Sleep Study for Children With Down Syndrome - In Lab and At Home

Social Coordination

Somatosensory Evoked Potentials at Different Positions in children with cerebral palsy

SPARK: Simons Foundation Powering Autism Research for Knowledge

Stem Cell Transplant for Sickle Cell Disease or Thalassemia Major

Structural Development of Human Infant Brain

Study of Breathing During Sleep in Infants with Micrognathia and Healthy Infants

Study of Efficacy and Safety of Tisagenlecleucel in Children and Young Adults with HR B-ALL that is end-consolidation MRD Positive (AALL1721/CASSIOPEIA)

Study of Rifampin as a Treatment for Elevated Calcium Levels in Patients with Genetic Vitamin D Excess

Study on Brain Responses During Simulated Driving

SECURE-VA Registry

T

T2017-002 TACL Ixazomib Study

TACL-2020-003; IDEAL2 Study

TAS-117 in Tumors Harboring Germline PTEN Inactivating Mutations

Tasty and Healthy

Telemedicine in Early Childhood Constraint Therapy in Cerebral Palsy

Teplizumab in New-Onset Type 1 Diabetes

The CARRA Registry

The Charisma Study

The Myelin Disorders Biorepository Project (MDBP)

The SLEEPY Study

The Virtual Growing Child

Therapeutic use of Tadekinig alfa in NLRC4 mutation and XIAP deficiency

Thyroidectomies

TII (Treating IBD with Inulin)

Topical Sirolimus for Microcystic Lymphatic Malformations

TransPrEP Phase 3: 3T Intervention

Trial of Erenumab for Preventive Treatment of Pediatric migraine 15 days per month or more

Trial of Erenumab in Children and Teens with Migraine less than 15 days per month

U

Upadacitinib Trial for Polyarticular JIA

UX053 in GSD III

V

Visual Measures in Pediatric MS

Vitamin E Supplementation in Hyperinsulinism/Hyperammonemia (HI/HA) Syndrome

Vocal Biomarkers of Autism Spectrum Disorder

VR Intervention to Improve Police Safety

W

Walking and Talking in Autism

What Do You Eat? An Online Study for Youth with ASD