Imaging Cognition and Neurodevelopment (ICAN)



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The purpose of this research study is to examine relationships between brain and behavior development in toddlers with and without autism who have older siblings.

You may qualify for our study if you or your child's healthcare provider has concerns regarding your toddler's development (communication, motor, behavior, or social concerns or developmental concerns). Toddlers must have older biological sibling(s) without autism.

Who Do I Contact?

If you are interested in participating in the study or want to learn more please contact our study team at ican [at] or 267-425-1139.

Eligibility & Criteria

IRB #:
Official Title:
A Longitudinal MRI Study of Toddlers With Simplex Autism
Study Phase:
Eligible Age Range:
16 -20 Months
Study Categories:
Downloadable Resources:


Visit Criteria

Your participation would involve you coming to the Center for Autism Research at CHOP in Philadelphia with your toddler.

There are four parts involved in your participation:

  1. A remote video call interview with you and our study's clinical psychologist.
  2. Online questionnaires which you will complete on your own time on any internet device.
  3. A behavioral evaluation of your toddler. For this part, you will first visit the Center for Autism Research with just you and your toddler. After this behavior evaluation, we will schedule a follow-up video call with you, where the psychologist will inform you about the testing results.
  4. If your child meets our criteria, we will ask you to return for an MRI scan of your toddler's brain while they sleep.

You will be compensated for your time and effort dedicated to the study and you will be reimbursed for your travel expenses to CHOP.