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CCMT Seminar Series - March 9



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Mar 9, 2023
Event Start Time
11:00 am to
Event End Time
12:00 pm
Location - People View

3501 Civic Center Blvd
Philadelphia, PA 19104
United States

The Raymond G. Perelman Center for Cellular and Molecular Therapeutics at CHOP presents a Lecture Series:

A Stressful Beginning: DNA Replication in the Mammalian Embryo


Dieter Egli, PhD

Associate Professor of Cell and Developmental Biology

Department of Pediatrics

Naomi Berrie Diabetes Center

Columbia Stem Cell Initiative

Department of Obstetrics and Gynecology

Columbia University

Description of Research

DNA replication is not usually thought of as a cell-type specific process because of a constant result, the duplication of the entire genome. Cellular phenotypes are generally viewed through the lens of transcriptional differences, rather than differences in DNA replication. However, genome integrity is required for cell cycle progression, and there are both locus as well as cell-type specific differences in DNA replication and genome stability. The functional significance of these differences are still poorly understood. Dr. Egli will present progress on studies on DNA replication in the early mammalian embryo, and genomic methods of analysis of DNA replication.


Kai Wang, PhD

Please email if you would like to meet with the speaker.

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