Division of Rheumatology

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Rheumatic diseases present a particular clinical challenge due to their rarity, complexity, and chronicity. These challenges represent opportunities for improvement that are realized through the robust research program in the Division of Rheumatology, which involves work across the spectrum of basic science to clinical research domains.

The Division's flourishing program has become widely recognized as a premiere location for innovative and impactful pediatric rheumatology research in the nation. This program addresses epidemiologic and clinical research with an aim of optimizing patient care with the most state-of-the-art clinical tools. Research in the laboratory delves into the basic, fundamental science that informs the causes and mechanisms of disease in order to develop the next generation of clinical tools.

Research in the Division of Rheumatology generally focuses on the causes of rare, orphan inflammatory diseases; chronic autoimmune disease as it crosses from pediatric to adult presentations; the means to leverage basic immunology to develop new cures; and the pioneering use of genetic information to drive individualized medical decision making, coupled with population management tools to increase the precision with which care is delivered.

Among the Division’s specific research strengths are its robust and innovative programs in amplified pain, which represents the leading program in the nation; juvenile idiopathic arthritis, particularly spondyloarthropathies and tools within the electronic medical record that provide investigators in the Division with a unique research platform; a dedicated and growing program in lupus research; and expertise in rare autoinflammatory disease and the management of cytokine storm syndromes.