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De León-Crutchlow Laboratory Research Studies

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HM15136 for the Treatment of Congenital Hyperinsulinism Research Study

The purpose of this study is to look at the safety and tolerability (how well you will react) of the study drug (HM15136) and to determine if it is effective for the treatment of Congenital Hyperinsulinism (HI).

Related Conditions:
Hyperinsulinism, Hypoglycemia, Endocrinology Disorders, Clinical Trials, Beta Cell Dysfunction, Pediatric Endocrinology, Rare Disorder Natural History Studies and Clinical Trials, Rare Disease, Insulin Dysfunction, Pancreas Dysfunction, Beta Cell Dysfunction
This study is actively recruiting.

Moderna mRNA Clinical Trial for Patients with GSD 1a

Moderna mRNA Clinical Trial for Patients with GSD 1a

Our team has partnered with Moderna on a clinical trial for patients with glycogen storage disease type 1a (GSD1a).

Related Conditions:
Glucose Metabolism, Hypoglycemia
This study is actively recruiting.

Neurocognition in Hyperinsulinism

Neurocognition in Hyperinsulinism

The purpose of this study is to understand how cognitive function changes over time in children with hyperinsulinism (HI) compared to children who are healthy volunteers.

Related Conditions:
Congenital Hyperinsulinism, Endocrinology Disorders, Hyperinsulinism, Insulin Dysfunction, Pancreas
This study is actively recruiting.

Phenotyping Congenital Hyperinsulinism

Phenotyping Congenital Hyperinsulinism

The Congenital Hyperinsulinism Center at the Children's Hospital of Philadelphia is working on a research study to better understand how people with hyperinsulinism may have different blood sugar responses to certain tests (like fasting or drinking a high-protein shake) when compared to people without hyperinsulinism.

Related Conditions:
Hyperinsulinism, Hypoglycemia, Insulin Dysfunction, Pancreas Dysfunction, Endocrinology Disorders, Glucose Metabolism, Glucose Intolerance, Genetic Disease, Rare Disease, Pediatric Endocrinology, Rare Disorder Natural History Studies and Clinical Trials
This study is actively recruiting.

Research Study for Individuals with Hyperinsulinism, Type 1 Diabetes Mellitus, and Healthy Children

Research Study for Individuals with Hyperinsulinism, Type 1 Diabetes Mellitus, and Healthy Children

Our team is working on a study to better understand neurological problems, including seizures and developmental delays, that occur in children with hyperinsulinism, including HI/HA syndrome, and type 1 diabetes mellitus.

Related Conditions:
Hyperinsulinism, Hypoglycemia, Insulin Dysfunction, Pancreas Dysfunction, Endocrinology Disorders, Neuroendocrinology, Neuroimaging, Glucose Metabolism, Rare Disease, Rare Disorder Natural History Studies and Clinical Trials, Pediatric Endocrinology
This study is actively recruiting.

sunRIZE Study: RZ358 Clinical Trial for Hyperinsulinism

This clinical trial is for patients with congenital hyperinsulinism (HI) who are experiencing low blood sugar on their current treatment.

Related Conditions:
Beta Cell Dysfunction, Clinical Trials, Congenital Hyperinsulinism, Endocrinology, Endocrinology Disorders, Glucose Metabolism, Hyperinsulinism, Insulin Dysfunction, Pediatric Beta Cell Disease, Pediatric Clinical Trials, Pediatric Endocrinology, Rare Disease, Rare Diseases, Rare Disorder Natural History Studies and Clinical Trials, Surgical Treatment of Hyperinsulinism
This study is actively recruiting.