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CVI News: Drs. Jolley and Pei Receive Single Ventricle Research Fund Grants

Published on March 20, 2023 · Last Updated 2 months 1 week ago


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Matthew Jolley, MD, assistant professor and attending physician in the Center for Pediatric Heart Valve Disorders, and Liming Pei, PhD, investigator in the Department of Pathology and Laboratory Medicine received grants through the 2022 Single Ventricle Research Fund (SVRF), offered by Additional Ventures. The program supports researchers who seek to advance the care of patients with single ventricle heart defects through researching key areas of genetics, cardiovascular development, and computational models.

The SVRF recognized Dr. Jolley for his research surrounding the use of image-derived computational modeling to assist in valve repair in children with congenital heart disease. His team aimed to create an open-source computational framework for image-derived valve analysis that brought together two open-source tools: modeling platform SlicerHeart and modeling software FEBio.

Dr. Pei, who is also an associate professor of Pathology and Laboratory Medicine at Penn, received support for his research on Fontan circulation as a strategy for care of single ventricle congenital heart disease. His work examines the possibly life-threatening complications that arise from this method of care, most notably hepatic fibrosis, also known as Fontan-associated liver disease.

View the SVRF announcement to learn more about the 2022 grant recipients.