Comprehensive Bone Marrow Failure Center Publications



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Below is a list of selected publications from the Comprehensive Bone Marrow Failure Center:

Shah YB, Priore SF, Li Y, Tang CN, Nicholas P, Kurre P, Olson TS, Babushok DV. The predictive value of PNH clones, 6p CN-LOH, and clonal TCR gene rearrangement for aplastic anemia diagnosis. Blood Adv. 2021 Aug; 5(16):3216-3226. doi: 10.1182/bloodadvances.2021004201. PMID: 34427585
Hurwitz SN, Jung SK, Kurre P. Hematopoietic stem and progenitor cell signaling in the niche. Leukemia. 2020 Dec; 34(12):3136-3148. Epub 2020 Oct 19. PMID: 33077865
Oved JH, Babushok DV, Lambert MP, Wolfset N, Kowalska MA, Poncz M, Karczewski KJ, Olson TS. Human mutational constraint as a tool to understand biology of rare and emerging bone marrow failure syndromes. Blood Adv. 2020 Oct; 4(20):5232-5245. PMID: 33104793
Babushok DV, Nelson EJ, Morrissette JJD, Joshi S, Palmer MB, Frank D, Cambor CL, Hexner EO. Myelofibrosis patients can develop extramedullary complications including renal amyloidosis and sclerosing hematopoietic tumor while otherwise meeting traditional measures of ruxolitinib response. Leuk Lymphoma. 2020 Mar; 60(3):852-855. PMID: 30227762
Robino JJ, Pamir N, Rosario S, Crawford LB, Burwitz BJ, Roberts CT Jr, Kurre P, Varlamov O. Spatial and biochemical interactions between bone marrow adipose tissue and hematopoietic stem and progenitor cells in rhesus macaques. Clin Infect Dis. 2019 May; 68(12):2003-2009. PMID: 30256954
Ganetsky A, Han JH, Hughes ME, Babushok DV, Frey NV, Gill SI, Hexner EO, Loren AW, Luger SM, Mangan JK, Martin ME, Smith J, Freyer CW, Gilmar C, Schuster M, Stadtmauer EA, Porter DL. Oral vancomycin prophylaxis is highly effective in preventing Clostridium difficile infection in allogeneic hematopoietic cell transplant recipients. Clin Infect Dis. 2019 May; 68(12):2003-2009. PMID: 30256954
Ganetsky A, Frey NV, Hexner EO, Loren AW, Gill SI, Luger SM, Mangan JK, Martin ME, Babushok DV, Drobyski WR, Smith J, Timlin C, Freyer CW, Stadtmauer EA, Porter DL. Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract. Bone Marrow Transplant. 2019 Feb; 54(2):212-217. PMID: 29795429
Babushok DV, Stanley NL, Morrissette JJD, Lieberman DB, Olson TS, Chou ST, Hexner EO. Germline duplication of ATG2B and GSKIP genes is not required for the familial myeloid malignancy syndrome associated with the duplication of chromosome 14q32. Leukemia. 2018 Dec; 32(12):2720-2723. PMID: 30087419
Babushok DV. A brief, but comprehensive, guide to clonal evolution in aplastic anemia. Hematology Am Soc Hematol Educ Program. 2018 Nov; 2018(1):457-466. PMID: 30504346
Oved JH, Wang Y, Barrett DM, Levy EM, Huang Y, Monos DS, Grupp SA, Bunin NJ, Olson TS. CD3+/CD19+ Depleted Matched and Mismatched Unrelated Donor Hematopoietic Stem Cell Transplant with Targeted T Cell Addback Is Associated with Excellent Outcomes in Pediatric Patients with Nonmalignant Hematologic Disorders. Biol Blood Marrow Transplant. 2018 Oct; pii: S1083-8791(18)30612-8. doi: 10.1016/j.bbmt.2018.10.003. [Epub ahead of print] PMID: 30312755
Doron B, Abdelhamed S, Butler JT, Hashmi SK, Horton TM, Kurre P. Transmissible ER stress reconfigures the AML bone marrow compartment. Leukemia. 2018 Apr; 33(4):918-930. PMID: 30206307
Babushok DV, Duke JL, Xie HM, Stanley N, Atienza J, Perdigones N, Nicholas P, Ferriola D, Li Y, Huang H, Ye W, Morrissette JJD, Kearns J, Porter DL, Podsakoff GM, Eisenlohr LC, Biegel JA, Chou ST, Monos DS, Bessler M, and Olson TS. Somatic HLA Mutations Expose the Role of Class I-Mediated Autoimmunity in Aplastic Anemia and its Clonal Complications. Blood Adv. 2017 Oct; 1(22):1900-1910. PMID: 28971166
Yoon YM, Storm KJ, Kamimae-Lanning AN, Goloviznina NA, Kurre P. Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2(-/-) Hematopoietic Stem and Progenitor Cells. Stem Cell Reports. 2016 Nov; 7(5):840-853. PMID: 27720904
Chakkaramakkil VS, Goloviznina NA, Kurre P. Phenotypic correction of Fanconi anemia cells in the murine bone marrow after carrier cell mediated delivery of lentiviral vector. Stem Cell Res Ther. 2016 Nov; 7(1): 170, PMCID: PMC5116221
Hornick N, Doron B, Abdelhamed S, Huan J, Harrington C, Shen R, Cambronne X, Verghese S, Kurre P. AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB. Science Signaling. 2016 Sep; 9(444). PMID: 27601730
Babushok, DV, Bessler M, and Olson TS. Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults. Leuk Lymphoma. 2016 Jan; 57(3):520-36. PMCID: PMC4798888
Betensky M, Babushok D, Roth JJ, Mason, PJ, Biegel JA, Busse TM, Li Y, Lind C, Papazoglou A, Monos D, Podsakoff G, Bessler M, and Olson TS. Clonal evolution and clinical significance of copy number neutral loss of heterozygosity of chromosome arm 6p in acquired aplastic anemia. Cancer Genet. 2016 Jan; 209(1-2):1-10. PMID: 26702937