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CCCR News & Announcements
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Published on May 7, 2025 in Cornerstone Blog
Using advanced omics and computational techniques, the researchers found that both cancer and immune cells changed after treatment.
Published on Apr 9, 2025 in Cornerstone Blog
Jessica Foster, MD, this month’s Faculty Spotlight, is working hard to bring immunotherapy treatments for brain and spinal cord tumors from bench to bedside.
Published on Apr 3, 2025 in Cornerstone Blog
PEEL-224, a therapy to treat high-risk tumors, enters a pediatric clinical trial after a decade of groundbreaking research.
Published on Mar 31, 2025 in Cornerstone Blog
Meet seven women in STEM at CHOP Research Institute nominated by their Centers of Emphasis for their excellence and inspiration.
Published on Mar 17, 2025 in Cornerstone Blog
Researchers from CHOP and Penn find combination therapy could support efficacy of CAR T-cell therapy in treating acute myeloid leukemia.
Published on Mar 7, 2025 in Cornerstone Blog
STAT Madness selects CHOP-led research on hemophilia A gene therapy for the bracket competition, and two scientists are nominated as "Disruptors of the Year."
Published on Jan 24, 2025 in Cornerstone Blog
Dr. Stephan Grupp attends Cell and Gene Therapy Forum at the White House, and CHOP Research Institute supports early-career investigators. This and more In The News.
Published on Jan 6, 2025 in Cornerstone Blog
The CHOP-led trial showed that blinatumomab plus chemotherapy drastically improved survival rates for patients with B-ALL.
Published on Dec 30, 2024 in Cornerstone Blog
We tallied up the most popular Cornerstone blog stories of 2024 based on data across our CHOP Research social media platforms.
Published on Dec 19, 2024 in Cornerstone Blog
As the pediatric cancer charity celebrates its 20th anniversary, Cornerstone is highlighting the groundbreaking research at CHOP fueled by two decades of collaboration.
Published on Nov 6, 2024 in Cornerstone Blog
Researchers identify cell surface protein DLK1 as a potential immunotherapeutic target for neuroblastoma.
Published on Oct 16, 2024 in Cornerstone Blog
The Pennsylvania Department of Health CURE grant will help researchers understand why treatment fails some children with B-ALL and helps others.
Published on Sep 30, 2024 in Cornerstone Blog
CHOP researchers uncovered 15 subtypes of T-cell acute lymphoblastic leukemia, which will help to predict outcomes and guide treatment.
Published on Aug 30, 2024 in Cornerstone Blog
CHOP researchers gain a new understanding of the genetic drivers of T-ALL, a particularly challenging childhood cancer.
Published on Aug 23, 2024 in Cornerstone Blog
Grab your pompoms and get your game face on as we go Off Campus to Lincoln Financial Field with CHOP research technician Makenna Higgins.
Published on Aug 16, 2024 in Cornerstone Blog
Two CHOP fellows join the Pediatric Scientist Development Program, AI offers timely diagnosis of genetic epilepsies, and more in this week’s news.
Published on Jun 26, 2024 in Cornerstone Blog
Three CHOP investigators help amplify the voices of the LGBTQIAS2S+ scientific community in this preview of the video series.
Published on Jun 21, 2024 in Cornerstone Blog
Discover new tools that streamline germline classification and cluster patterns in spatial transcriptomics data in this week’s research news.
Published on Jun 3, 2024 in Press Releases
John Maris, MD, the Giulio D’Angio Endowed Chair in Neuroblastoma Research at CHOP, is this year’s recipient of the Alex’s Lemonade Stand Pitcher of Hope Award.
Published on Apr 26, 2024 in Cornerstone Blog
News highlights this week include the Biomedical Technician Training Program recognition event, new COVID-19 outcomes research, and more.
Published on Apr 10, 2024 in Cornerstone Blog
Evan Weber, PhD, and a research team from CHOP and Stanford Medicine discovered that the protein FOXO1 plays a key role in regulating CAR T cells’ longevity and effectiveness.
Published on Mar 18, 2024 in Cornerstone Blog
Eight women in STEM at CHOP share their experiences in the field, current work, and advice for aspiring scientists.
Published on Feb 19, 2024 in Cornerstone Blog
With the help of an artificial intelligence deep-learning algorithm called CytoCommunity, researchers better understand how specific cell groups in tissues organize to support tissue function.
Published on Jan 30, 2024 in Cornerstone Blog
Dr. Maris is co-leading a study that aims to develop patient-specific cancer vaccines that could be applied to patients in remission to prevent relapse.
Published on Jan 19, 2024 in Cornerstone Blog
In The News highlights findings on COVID-19 vaccination and children, pediatric underinsurance, and a glimpse into how cancer cells interact with each other.
Published on Dec 28, 2023 in Cornerstone Blog
These six stories received the highest number of engagements on CHOP Research social media channels in 2023.
Published on Dec 8, 2023 in Cornerstone Blog
Our research news roundup highlights the improvements made in CAR therapies through structural biology discoveries and cost reduction strategies.
Published on Sep 26, 2023 in Cornerstone Blog
Annual long-term follow-up care is critical to manage and monitor for late effects, recurrence, or new cancer.
Published on Sep 18, 2023 in Cornerstone Blog
Congratulations to the 2023 Carole Marcus Award Recipients: Stella Chou, MD, and Lisa Schwartz, PhD.
Published on Sep 8, 2023 in Cornerstone Blog
Sarah K. Tasian, MD, received a $1 million grant to further her research into a novel immunotherapy for high-risk pediatric leukemias.
Published on Sep 1, 2023 in Cornerstone Blog
This week’s news roundup features three studies, Doris Duke Award winners, and a commitment to the CHOP Parkway Run & Walk.
Published on May 18, 2023 in Cornerstone Blog
Scientists from Children’s Hospital of Philadelphia attend the American Society of Cell & Gene Therapy Annual Meeting to share their expertise through posters, panel discussions, and workshops.
Published on Apr 26, 2023 in Press Releases
Two recent papers from CHOP cancer researchers have advanced the understanding of treatment-resistant pediatric central nervous system tumors.
Published on Apr 14, 2023 in Cornerstone Blog
Learn about a technique to analyze large datasets, preclinical results that show safety and efficacy of a drug that could help children with high-risk neuroblastoma, and a milestone in the CORSICA project that seeks to cure rare sinonasal cancers.
Published on Mar 20, 2023 in Cornerstone Blog
We’re celebrating Women’s History Month by highlighting 10 women working in STEM fields who were nominated by their Center of Emphasis leaders.
Published on Jan 27, 2023 in Cornerstone Blog
By studying the molecular basis of pediatric thyroid cancer, Dr. Franco seeks to improve outcomes and quality of life for patients.
Published on Jan 19, 2023 in Cornerstone Blog
In this Q&A, Drs. Teachey and Diorio discuss their partnership and research of a novel CAR T-cell therapy for one of the most common pediatric cancers.
Published on Dec 29, 2022 in Cornerstone Blog
These six Cornerstone stories garnered the most engagements from our CHOP Research Twitter, Facebook, and LinkedIn channels.
Published on Dec 9, 2022 in Cornerstone Blog
This week's news roundup features an outstanding science award, Highly Cited Researchers, and STAT Wunderkinds, along with new research about cancer risk with birth defects, epilepsy, and acute myeloid leukemia.
Published on Nov 25, 2022 in Cornerstone Blog
The work of Children’s Hospital of Philadelphia researchers leads to novel findings and recognitions.
CHOP Researchers Show Liquid Biopsies Can Catch Disease Progression Early in High-Risk Neuroblastoma
Published on Nov 14, 2022 in Press Releases
Liquid biopsies can less invasively and more accurately identify tumor changes in patients with high-risk neuroblastoma.
Published on Sep 16, 2022 in Cornerstone Blog
This week’s In the News highlights research on mitochondrial disease, acute lymphoblastic leukemia, type 2 diabetes, and sleep apnea.
Published on Aug 9, 2022 in Cornerstone Blog
Children’s Hospital of Philadelphia has a leading role in the NCI’s plan to streamline drug development for childhood cancers.
Published on Aug 5, 2022 in Cornerstone Blog
This week’s In the News highlights PolicyLab’s second annual Impact Report, an FDA approval based on CHOP research, and a link between daycare and chronic lung disease effects in premature infants.
Published on Jun 29, 2022 in Cornerstone Blog
CHOP scientists are part of a Cancer Grand Challenges team receiving $25 million to tackle solid tumors.
Published on Jun 16, 2022 in Press Releases
Four CHOP researchers are part of a world-class research team that will receive $25 million to study solid tumors in children, funded by Cancer Grand Challenges.
Published on Jun 8, 2022 in Cornerstone Blog
CHOP researchers are leading IAMFIT, a clinical study testing an exercise intervention to enhance lifelong health for young HCT survivors.
Published on May 27, 2022 in Cornerstone Blog
Learn about novel findings and notable achievements from our Children’s Hospital of Philadelphia researchers.
Published on May 23, 2022 in Press Releases
CHOP researchers have tested and developed an “off-the-shelf” chimeric antigen receptor T-cell (CART) using base editing.
Published on May 23, 2022 in Press Releases
CHOP, Penn, Costa Rica: International collaboration aims to ensure more equitable access to transformative personalized cancer therapy
Published on May 13, 2022 in Cornerstone Blog
This week’s In the News highlights young cancer survivors, COVID-19, awards for two CHOP oncologists, and a tool to evaluate cancer mutations.
Published on May 5, 2022 in Press Releases
Two Oncologists within the Cancer Center were recognized at the 2022 ASPHO Conference.
Published on Apr 4, 2022 in Cornerstone Blog
Researchers at CHOP found that bortezomib improve survival in children with T-cell lymphoblastic lymphoma.
Published on Mar 28, 2022 in Cornerstone Blog
The Susan S. and Stephen P. Kelly Center for Cancer Immunotherapy is a first-of-its-kind hub for pediatric Cancer Immunotherapy.
Published on Mar 14, 2022 in Press Releases
Linking a tumor-killing prodrug to a macromolecular carrier of the Poloxamer family improved retention of the drug in treatment-resistant neuroblastoma tumors.
Published on Jan 28, 2022 in Cornerstone Blog
World-class experts will gather at CHOP summit to present on scientific advances in pediatric cancer care in the diagnostics and therapeutic space.
Published on Jan 3, 2022 in Cornerstone Blog
Congratulations to Garrett Brodeur, MD, recipient of the American Society of Pediatric Hematology/Oncology Distinguished Career Award.
Published on Dec 30, 2021 in Cornerstone Blog
Here’s our list of the 2021 Cornerstone stories our social media followers engaged with the most.
Published on Dec 15, 2021 in Cornerstone Blog
Dr. Mark Yarmarkovich, PhD, a senior scientist at CHOP, is a 2021 STAT Wunderkind.
Published on Dec 10, 2021 in Cornerstone Blog
Our research news highlights a study about sequencing bone marrow DNA after CAR T-cell therapy and how it accurately predicts leukemia relapse.
Published on Dec 1, 2021 in Press Releases
Next-generation DNA sequencing can predict relapse of patients with acute lymphoblastic leukemia treated with (CAR) T-cell therapy.
Published on Nov 3, 2021 in Cornerstone Blog
The peptide-centric CAR T cells, or PC-CARS, target cancer drivers in tumor cells previously thought unreachable.
Published on Aug 20, 2021 in Cornerstone Blog
This week in the news, we share findings on Fontan circulation side effects, pediatric brain tumor survivorship, gene therapy, and more.
Published on Aug 6, 2021 in Cornerstone Blog
This week’s research news features Dr. Audrey Odom John and her discovery of six breath compounds that could lead to a COVID breathalyzer for kids.
Published on Aug 2, 2021 in Press Releases
CHOP is proud to announce Dr. Garrett Brodeur was honored with the Distinguished Career Award from the American Society of Pediatric Hematology/Oncology.
Published on Jul 15, 2021 in Cornerstone Blog
Kathrin Bernt, MD, spends her workdays investigating blood cancers and her off campus hours riding Thor, her pandemic horse.
Published on Jul 9, 2021 in Cornerstone Blog
This week’s news roundup features new findings in youth suicide risk, CAR T-cell therapy, obesity rates during the pandemic, and more.
Published on Jun 28, 2021 in Press Releases
The results of the phase 1 study were published in the Journal of Clinical Oncology.
Published on May 26, 2021 in Cornerstone Blog
The 17th Research Institute Scientific Symposium, held virtually on May 20, highlighted advances in cell and gene therapy.
Published on May 24, 2021 in Cornerstone Blog
A previously unreported immunodeficiency disease prevents the formation of the B cells and antibodies that help fight off infections.
Published on May 19, 2021 in Cornerstone Blog
CHOP Researchers find the novel mechanistic link by which MNI causes acute myeloid leukemia.
Published on May 14, 2021 in Cornerstone Blog
This week’s research news features Ran Barzilay, PhD, and the results of the latest COVID-19 Resilience Project from the Lifespan Brain Institute.
Published on May 12, 2021 in Press Releases
Four CHOP gene therapy experts were interviewed as part of a comprehensive article in Philadelphia Magazine about cell and gene therapy.
Published on Apr 29, 2021 in Cornerstone Blog
CHOP Researchers received a grant from the NCI to investigate a novel treatment for high-risk neuroblastoma.
Published on Apr 16, 2021 in Cornerstone Blog
This week’s news round-up highlights several researcher awards, and funding for D3B and neuroblastoma research
Published on Apr 9, 2021 in Press Releases
The award was presented to the St. Baldrick’s Foundation-Stand Up 2 Cancer Pediatric Cancer Dream Team, co-led by CHOP.
Published on Apr 2, 2021 in Cornerstone Blog
This week’s research news features Kathrin Bernt, MD, and Richard Aplenc, MD, PhD, MSCE, recipients of Children’s Cancer Research Fund Awards.
Published on Mar 19, 2021 in Cornerstone Blog
In this research news roundup, new insights from the HERO registry, a targeted treatment for high-risk relapsed B-ALL, and more.
Published on Mar 16, 2021 in Press Releases
The grant funds the development of a drug that targets a transcription factor that drives aggressive pediatric cancers.
Published on Mar 10, 2021 in Cornerstone Blog
We feature seven more women in STEM at CHOP nominated by leaders of their Centers of Emphasis.
Published on Mar 8, 2021 in Cornerstone Blog
Nominated by their Centers of Emphasis, women in STEM share what drives them, their words of wisdom, and why they do what they do.
Published on Mar 5, 2021 in Press Releases
A new study shows blinatumomab is less toxic and as good or better than chemotherapy for high-risk relapsed B-ALL.
Published on Feb 19, 2021 in Cornerstone Blog
This week’s research news features CHOP Oncologist Stephen Hunger, MD, as quoted in a “TODAY Show” article about pediatric cancer research.
Published on Jan 8, 2021 in Cornerstone Blog
This week’s research news features CHOP’s participation in a study that found outcome disparities by race/ethnicity in children with severe sepsis.
Published on Nov 20, 2020 in Press Releases
By targeting a genetic pathway using an existing drug used in a previous case, the researchers remodeled the patient’s lymphatic system.
Published on Sep 11, 2020 in Cornerstone Blog
This week’s roundup features research exploring the value of well care as voiced by Black adolescent males and their parents. This and more In The News.
Published on Sep 10, 2020 in Cornerstone Blog
Researchers published the first report of pediatric patients treated with convalescent plasma for SARS-CoV-2 associated acute respiratory distress syndrome.
Published on Aug 24, 2020 in Press Releases
CHOP-engineered therapy overcomes common drug resistance and has potential to elicit fewer toxicities than most cancer treatments.
Published on Aug 10, 2020 in Cornerstone Blog
A new Center of Emphasis will develop and share single cell technologies as a major approach to basic and translational research.
Published on Jul 22, 2020 in Cornerstone Blog
Dr. Patrick Grohar, director for Translational Research with the Center for Childhood Cancer Research, discusses development of a treatment for Ewing sarcoma.
Published on Jun 11, 2020 in Cornerstone Blog
Neuroblastoma researchers shift their work toward strategizing a safe, effective vaccine against SARS-CoV-2.
Published on Jun 4, 2020 in Press Releases
A CHOP study revealed immune biomarkers that indicate whether a patient might respond well to immunotherapy for AML.
Published on May 4, 2020 in Cornerstone Blog
A multidisciplinary team of physician-researchers at CHOP are studying the role of cytokine storms in COVID-19.
Published on Mar 26, 2020 in Cornerstone Blog
Our second installment of Women in STEM features more scientists leading fields historically underrepresented by women.
Published on Feb 10, 2020 in Cornerstone Blog
New research utilizes eye-tracking technology to study visual social attention in pediatric brain tumor survivors.
Published on Jan 31, 2020 in Cornerstone Blog
MOMS2 study findings show benefits of prenatal surgery for spina bifida continue to childhood. This and more In the News.
Published on Jan 17, 2020 in Cornerstone Blog
In this week’s news roundup, our researchers approach challenges in children’s health research from a new lens.
Published on Dec 31, 2019 in Cornerstone Blog
We peeked into the data to see which research stories captivated our readers the most in 2019: Here are the top five.
Published on Jan 11, 2019 in Cornerstone Blog
“Please play your video game,” said parents — never. Find out why this phrase may become common among caregivers of children with autism and ADHD.
Published on Dec 31, 2018 in Cornerstone Blog
We peeked into our data to see which research stories captivated our readers the most in 2018: Here are our top six.
Published on Dec 28, 2018 in Cornerstone Blog
In this week’s roundup, CHOP launches a partnership to help the most vulnerable kids with asthma, and research supports a holistic approach to recovery from violence.
Published on Dec 10, 2018 in Cornerstone Blog
Investigators in the Center for Childhood Cancer Research have received a five-year grant totaling more than $12.5 million to develop the Center for Pediatric Tumor Cell Atlas.
Published on Oct 2, 2018 in Press Releases
The 2018 Parkway Run & Walk raised a record-breaking $1.38 million — and counting — to support breakthroughs in pediatric cancer research and care at Children's Hospital of Philadelphia (CHOP).
Published on Sep 24, 2018 in Cornerstone Blog
On World Cancer Research Day, our blog goes to the Dominican Republic, where fellow Julianne Burns, MD, embarked on much needed infectious disease research.
Published on Sep 7, 2018 in Cornerstone Blog
We usher in Childhood Cancer Awareness Month with headlines that highlight the impact of our cancer breakthroughs.
Published on Jun 27, 2018 in Cornerstone Blog
In a Q&A, Division of Oncology Chief Stephen P. Hunger, MD, shares what inspires him to conduct research on leukemia.
Published on Apr 20, 2018 in Cornerstone Blog
Learn about new grants and awards for our cancer researchers in this week's edition of In the News.
Published on Feb 26, 2018 in Cornerstone Blog
John Maris, MD, distinguished neuroblastoma researcher at CHOP, received the the National Cancer Institute's prestigious Outstanding Investigator Award.
Published on Sep 26, 2017 in Press Releases
CHOP scientists report on genetic links to neuroblastoma
Published on Jul 18, 2017 in Cornerstone Blog
Researchers from the Children's Oncology Group (COG) have developed a new standardized dosing method for anticancer drugs in infants to use across all COG clinical trials. This unified method, based on dose banding and organized into tables for different drugs and dose…
Published on Apr 7, 2017 in Cornerstone Blog
"Bold" is perhaps the best word to describe this week's roundup of Research Institute news, as Children's Hospital of Philadelphia nurses and investigators alike made headlines for their experimental work in pediatric CAR T-cell therapy: a cancer-fighting…
Published on Apr 4, 2017 in Cornerstone Blog
Childhood cancer still has its mysteries. Every specimen stored in the Center for Childhood Cancer Research (CCCR) Biorepository, however, is a precious piece of the puzzle: a gift of knowledge made possible by a Children's Hospital of Philadelphia patient's desire to…
Published on Jan 27, 2017 in Cornerstone Blog
Super Bowl Sunday is right around the corner, and our biweekly installment of In the News is the perfect playing field for us to showcase the wide range of research projects that Children's Hospital of Philadelphia experts tackle. Huddle up!
Published on Jan 13, 2017 in Cornerstone Blog
The year is off to a great start, with plenty of research news to report. This biweekly installment of In the News describes a new study in the emerging field of lymphatics, shares an editorial on advancements in neonatology, and highlights research to keep teen drivers safe.
Published on Dec 30, 2016 in Cornerstone Blog
The end of the year has come up fast, and so have important advances in pediatric research at Children's Hospital of Philadelphia. This week's In the News starts off with a celebration of two remarkable patients and their dedicated pediatric oncologist.
Published on Oct 28, 2016 in Cornerstone Blog
Although October is just ending, we're already looking ahead to the New Year in this week's installment of In the News.
Published on Oct 17, 2016 in Cornerstone Blog
By Bryan A. Wolf, MD, PhD, Chief Scientific Officer and Director of the Research Institute
Every space flight mission requires a carefully planned trajectory, and similarly the national Cancer Moonshot initiative needed a scientific roadmap to reach its ambitions…
Every space flight mission requires a carefully planned trajectory, and similarly the national Cancer Moonshot initiative needed a scientific roadmap to reach its ambitions…
Published on Mar 9, 2016 in Cornerstone Blog
Vice President Joe Biden’s ambitious “Moonshot” initiative is aimed at boosting and streamlining cancer research across the country. We asked Andrei Thomas-Tikhonenko, PhD, chief of the Division of Cancer Pathobiology and an investigator for the Center for Childhood Cancer…
Published on Jul 16, 2015 in Cornerstone Blog
The Children’s Hospital of Philadelphia Research Institute’s Office of Academic Training and Outreach Programs announced the selection of two new Research Administration fellows. Katherine Yang-Iott and Danika Johnston, PhD.
Published on Jun 1, 2015 in Cornerstone Blog
Researchers from CHOP are exploring how biodegradable nanoparticles can precisely deliver anticancer drugs to attack neuroblastoma, an often-deadly children’s cancer.
Published on May 27, 2015 in Cornerstone Blog
At the 13th Annual Dream & Promise Gala, set to be held tonight in New York, the Children’s Brain Tumor Foundation will honor Tom Curran, PhD, FRS, with the 2015 Fred J. Epstein, MD, Lifetime Achievement Award.
Published on Apr 20, 2015 in Cornerstone Blog
Stephen Hunger, MD and a team of researchers used highly sensitive deep sequencing techniques to see how genetic changes in acute lymphoblastic leukemia cells evolve from diagnosis to remission and relapse.
Published on Dec 23, 2014 in Cornerstone Blog
Stephen P. Hunger, MD, a nationally prominent specialist in children’s cancer, has been named the new director of the Center for Childhood Cancer Research (CCCR) and chief of the Division of Oncology.
Published on Nov 12, 2014 in Cornerstone Blog
A pediatric brain tumor expert and Deputy Scientific Director of the Research Institute, Dr. Curran was one of seventeen volunteers appointed to the PBTF’s newly created Research Advisory Network.
Published on Jul 8, 2014 in Cornerstone Blog
Australia’s 60 Minutes recently revisited its story from last year about the revolutionary immune therapy treatment spearheaded by The Children’s Hospital of Philadelphia’s Stephan A. Grupp, MD, PhD.
Published on Jul 3, 2014 in Cornerstone Blog
Teens with cancer often experience fatigue, pain, and other symptoms that can interfere with these personal goals, which psychologists refer to as health-related hindrance (HRH).
Published on May 27, 2014 in Cornerstone Blog
Dr. Grupp has received a great deal of attention for his investigation of using cell therapy to treat an aggressive form of childhood leukemia, acute lymphoblastic leukemia (ALL).
Published on May 6, 2014 in Cornerstone Blog
CHOP’s Center for Childhood Cancer Research (CCCR), has begun a unique collaboration that will contribute to scientific understanding of how immunotherapy can improve the survival of children with B cell acute lymphoblastic leukemia (B-ALL) that resists standard therapy.
Published on Dec 9, 2013 in Cornerstone Blog
The Children's Hospital of Philadelphia's groundbreaking leukemia research was on display at the recent American Society of Hematology (ASH) Annual Meeting. Held in New Orleans, the ASH Annual Meeting brought together approximately 20,000 researchers, clinicians, and…
Published on Nov 19, 2013 in Cornerstone Blog
The Children's Hospital of Philadelphia's Stephan A. Grupp, MD, PhD, along with his young patient Emily Whitehead, were recently named 2013 WebMD Health Heroes. The Center for Childhood Cancer Research's Director of Translational Research, Dr. Grupp has been…
Published on Oct 11, 2013 in Cornerstone Blog
Two recent awards to CHOP researchers show the incredible breadth of research being conducted at The Children's Hospital of Philadelphia Research Institute every day. Supported by the Pennsylvania Department of Health's Commonwealth Universal Research Enhancement…
Published on Sep 10, 2013 in Cornerstone Blog
The groundbreaking immune therapy work being done by The Children's of Hospital of Philadelphia's Stephan A. Grupp, MD, PhD, was recently highlighted on Australia's 60 Minutes. The Center for Childhood Cancer Research's Director of Translational Research, Dr…
Published on Jul 3, 2013 in Cornerstone Blog
A pediatric oncologist with the Cancer Center at The Children’s Hospital of Philadelphia recently received a national award highlighting his lifetime research on neuroblastoma, the most common solid tumor of childhood. The American Society of Clinical Oncology conferred one of…
Published on Apr 23, 2013 in Cornerstone Blog
A new genetic study offers glimpses into how scientists might use gene-sequencing data to customize pediatric patients' cancer treatments. While investigating the biology of brain tumors in children, researchers at The Children's Hospital of Philadelphia found that…
Published on Apr 10, 2013 in Cornerstone Blog
"The motivation for the creation of this collaborative research project is the realization that completely new strategies are needed if we are to have curative therapies for all childhood cancers," said Dr. Maris. A physician-researcher from The Children's…
Published on Mar 26, 2013 in Cornerstone Blog
The investigators, Stephen A. Grupp, MD, PhD and Carl H. June, MD, engineered T cells - the workhorses of the immune system, which recognized and attack invading disease cells - to selectively kill another type of immune cell called B cells, which had become cancerous.
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Published on Mar 7, 2013 in Cornerstone Blog
The innovative work being done by CHOP's Stephen Grupp, MD, was recently featured on the CBS show The Doctors. Dr. Grupp, the Center for Childhood Cancer Research's director of translational research, discussed his trial using immune therapy to treat an aggressive form…
Published on Jan 24, 2013 in Cornerstone Blog
A recent genomic study of neuroblastoma reinforces the challenges of treating the most aggressive forms of this disease. Contrary to expectations, the researchers found relatively few recurrent gene mutations - mutations that would suggest new targets for neuroblastoma treatment…
Published on Dec 12, 2012 in Cornerstone Blog
The holiday season is once again upon us! While it's a time for family and friends to gather, indulge in traditions, and celebrate this season of giving, it's also hard to believe another year has passed.
Published on Dec 9, 2012 in Cornerstone Blog
Dr. Stephen Grupp's patient, Emma, relapses with acute lymphoblastic leukemia (ALL) in April 2011. Cancer therapy for children has come a long way over the last several decades, and the cure rate for some forms of pediatric cancer is at an all-time high. Although this…