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CAG News & Announcements
Displaying announcements from the past three years.
1 - 101 of 101
Published on Jul 23, 2024 in Cornerstone Blog
16-year-old Balin is an active advocate for research and treatment of fibro-adipose vascular anomaly.
Published on Jun 21, 2024 in Cornerstone Blog
Discover new tools that streamline germline classification and cluster patterns in spatial transcriptomics data in this week’s research news.
Published on Jun 10, 2024 in Press Releases
By helping researchers cluster and analyze new data, new drug targets for rare diseases could be identified.
Published on Mar 18, 2024 in Cornerstone Blog
Eight women in STEM at CHOP share their experiences in the field, current work, and advice for aspiring scientists.
Published on Dec 8, 2023 in Cornerstone Blog
Our research news roundup highlights the improvements made in CAR therapies through structural biology discoveries and cost reduction strategies.
Published on Nov 28, 2023 in Press Releases
All three genes had variants affecting splicing and resulted in symptoms like developmental delays, intellectual disability, hypotonia, seizures and autism.
Published on Aug 16, 2023 in Announcements
Save the date the 2023 Joint Microbiome Symposium, Dec. 4-5.
Published on Aug 4, 2023 in Cornerstone Blog
Find out how CHOP researchers create a valuable impact on children’s health in the PolicyLab 2023 Impact Report and more in this week’s research news roundup.
Published on Jul 5, 2023 in Cornerstone Blog
A new deep sequencing method helps researchers identify and treat previously undetectable genetic mutations related to vascular anomalies.
Published on Mar 20, 2023 in Cornerstone Blog
We’re celebrating Women’s History Month by highlighting 10 women working in STEM fields who were nominated by their Center of Emphasis leaders.
Published on Mar 3, 2023 in Cornerstone Blog
In this news roundup, learn about the achievements of CHOP researchers from societal inductions to grant- and grand-prize recipients.
Published on Jan 30, 2023 in Cornerstone Blog
New software uses machine learning to analyze data about a single cell’s multiple characteristics.
Published on Jan 6, 2023 in Cornerstone Blog
See highlights of work by Children’s Hospital of Philadelphia researchers that is leading to novel findings.
Published on Dec 9, 2022 in Cornerstone Blog
This week's news roundup features an outstanding science award, Highly Cited Researchers, and STAT Wunderkinds, along with new research about cancer risk with birth defects, epilepsy, and acute myeloid leukemia.
Published on Nov 30, 2022 in Press Releases
Study on understudied non-chromosomal birth defects provides information critical to potential early detection of malignant tumors.
Published on Sep 16, 2022 in Cornerstone Blog
This week’s In the News highlights research on mitochondrial disease, acute lymphoblastic leukemia, type 2 diabetes, and sleep apnea.
Published on Aug 30, 2022 in Press Releases
First-of-its-kind study identifies differences between sexes as well as ethnic background.
Published on Jul 22, 2022 in Cornerstone Blog
Learn about novel findings from our Children’s Hospital of Philadelphia researchers.
Published on Jul 12, 2022 in Press Releases
The new algorithm could lead to improved outcomes of clinical trials and more targeted treatment.
Published on Jun 17, 2022 in Cornerstone Blog
Dr. Hakon Hakonarson has enjoyed riding horses since he was a young boy in Iceland.
Published on Feb 28, 2022 in Cornerstone Blog
From bench to bedside, Dr. Bhoj studies rare genetic disorders, particularly neurologic syndromes.
Published on Feb 18, 2022 in Cornerstone Blog
This week’s news roundup features CHOP’s Forbes’ ranking, a cancer research editorial by Madeline Bell, mask mandates, and mental disorders.
Published on Feb 1, 2022 in Press Releases
The deep learning model could help foster early intervention with better precision and a personalized approach to treatment.
Published on Sep 3, 2021 in Cornerstone Blog
This week’s In the News highlights two new studies, a new grant, the new director of the Cystic Fibrosis Center, and a physician’s new role.
Published on Aug 26, 2021 in Press Releases
The findings also show that these genetic markers are shared with autism spectrum, suggesting a possible connection.
Published on May 28, 2021 in Cornerstone Blog
This week’s news round-up features new discoveries in self-driving safety, genetic variants of neurodevelopmental disorders, and more.
Published on May 14, 2021 in Press Releases
Twelve patients have clinical features linked to the genetic variants, and preclinical models reveal more about how they affect normal function.
Published on May 14, 2021 in Cornerstone Blog
This week’s research news features Ran Barzilay, PhD, and the results of the latest COVID-19 Resilience Project from the Lifespan Brain Institute.
Published on Apr 2, 2021 in Cornerstone Blog
This week’s research news features Kathrin Bernt, MD, and Richard Aplenc, MD, PhD, MSCE, recipients of Children’s Cancer Research Fund Awards.
Published on Mar 23, 2021 in Press Releases
The supplement also proved effective at preventing the formation of amyloid proteins, which may lead to treatments for certain forms of dementia.
Published on Feb 11, 2021 in Cornerstone Blog
The 2020 Distinguished Research Trainee Award Recipients include trainees from a variety of levels and disciplines.
Published on Nov 20, 2020 in Press Releases
By targeting a genetic pathway using an existing drug used in a previous case, the researchers remodeled the patient’s lymphatic system.
Published on Sep 25, 2020 in Cornerstone Blog
In the News this week features concussion diagnosis in athletes, racial genetic differences in ADHD, COVID-19 projections, and more.
Published on Sep 21, 2020 in Press Releases
Using genome sequencing technology, researchers found potential causal mutations differ between ancestral groups, which may impact treatment.
Published on Sep 16, 2020 in Cornerstone Blog
Rare pediatric lung disease project supported by Doris Duke Charitable Foundation will help advance biorepository of lung specimens.
Published on Aug 19, 2020 in Cornerstone Blog
Researchers will study the mechanisms behind novel pediatric neurodegenerative disorders and assess their role in adult-onset conditions.
Published on Aug 14, 2020 in Cornerstone Blog
In the News this week features a Humanitarian Award, along with research on psychosis, antibiotics continuous glucose monitoring and DNA methylation.
Published on Aug 6, 2020 in Press Releases
Researchers from CHOP and NJIT developed an algorithm using machine learning that may help identify disease-causing mechanisms missed by conventional screening methods.
Published on Jul 27, 2020 in Cornerstone Blog
Center for Applied Genomics receives NIH funding to study the risk of disease in African Americans by combining genomic and environmental factors.
Published on Jul 2, 2020 in Cornerstone Blog
This week’s roundup features new thoughts on COVID-19 in children and novel findings on detecting seizures and preventing secondhand smoke.
Published on Jul 1, 2020 in Press Releases
Researchers received a multi-million dollar grant that focuses on the use of genomics to improve risk assessment for diverse populations.
Published on Apr 24, 2020 in Cornerstone Blog
This week’s roundup features new findings on early microbiome development, genetic variations in IBD, quality of life in ASD, and more.
Published on Apr 10, 2020 in Press Releases
Researchers at CHOP found a genetic mutation linked to inflammatory bowel disease.
Published on Jan 17, 2020 in Cornerstone Blog
In this week’s news roundup, our researchers approach challenges in children’s health research from a new lens.
Published on Dec 13, 2019 in Cornerstone Blog
Learn about developments in chromatin rebuilding, novel hemophilia treatment, linking heart and kidney disease, and genetic sequencing.
Published on Nov 19, 2019 in Cornerstone Blog
Using eMERGE Network data, researchers identified genome-wide significant loci that might be biomarkers for risk of cardiovascular disease.
Published on Jul 3, 2019 in Cornerstone Blog
Snapshot Science shares a collaborative science success story that helped a preteen with a genetic mutation that disrupted his lymphatic vessels.
Published on May 29, 2019 in Cornerstone Blog
The 2019 Scientific Symposium focused on the advances CHOP researchers have made in the booming area of genomics and data science.
Published on May 20, 2019 in Cornerstone Blog
Snapshot Science sums up largest-ever analysis of genetics and birth weight.
Published on Apr 12, 2019 in Cornerstone Blog
LiBI, a unique collaborative effort, bridges the gap between pediatric and adult research to learn how brain and behavior develop over a lifetime.
Published on Feb 8, 2019 in Cornerstone Blog
In this week’s recap, collaboration at the local and international levels takes center stage.
Published on Jan 23, 2019 in Press Releases
Children’s Hospital of Philadelphia (CHOP) scientists participated in a large international research consortium to discover and analyze genetic influences on common forms of epilepsy.
Published on Jan 11, 2019 in Cornerstone Blog
“Please play your video game,” said parents — never. Find out why this phrase may become common among caregivers of children with autism and ADHD.
Published on Oct 10, 2018 in Press Releases
CHOP Researcher: Findings may suggest more effective headache treatments
Published on Aug 28, 2018 in Press Releases
CHOP Researchers Report Potential Treatment that Restores Normal Anatomy in Animal Models
Published on Apr 18, 2018 in Cornerstone Blog
One person's autism can look very different from the next. Autism is a multifaceted spectrum disorder, so its underlying mechanisms and outward manifestations vary widely, with important implications for optimal treatment strategies.
Published on Mar 21, 2018 in Cornerstone Blog
Two-hundred attendees gathered for the first Lifespan Brain Institute Symposium to dig deep into the neurobiological development of mental illness.
Published on Mar 15, 2018 in Cornerstone Blog
Meet four women in science who are driving discovery at Children's Hospital of Philadelphia Research Institute.
Published on Mar 6, 2018 in Cornerstone Blog
CHOP researchers led an international team who found a new clue to a rare, genetic form of vitamin D-dependent rickets.
Published on Feb 28, 2018 in Cornerstone Blog
On Rare Disease Day, a guest blogger discusses the lack of high quality biospecimens for research and how our experts are working to change that.
Published on Feb 13, 2018 in Cornerstone Blog
Meet one of our three 2018 Diversity Fellows, Michael Gonzalez, PhD.
Published on Oct 6, 2017 in Cornerstone Blog
This week, new research findings at Children's Hospital of Philadelphia are propelling the way we think about autism, single ventricle survivors, and neuroblastoma forward.
Published on Sep 26, 2017 in Press Releases
CHOP scientists report on genetic links to neuroblastoma
Published on Aug 23, 2017 in Press Releases
CHOP Scientist: Ancient Mitochondrial DNA Genetic Patterns May Play Role in this Neurodevelopmental Condition
Published on Apr 13, 2017 in Cornerstone Blog
The Research Institute's Annual Report 2016, which you can find here, features dozens of inspiring and engaging stories that highlight new programs, our commitment to collaboration and excellence, and how our investigators and staff are leading the way in innovation and…
Published on Oct 7, 2016 in Cornerstone Blog
Welcome back to another weekly roundup of research news from the Children's Hospital of Philadelphia! Exciting and important pediatric research spans everything from conditions that are common and treatable, such as ear infections, to others more rare and deadly, such as…
Published on Oct 3, 2016 in Press Releases
In Largest Genomic Study to Date, CHOP Researchers Pinpoint Gene Variant in Acute Otitis Media
Published on Sep 16, 2016 in Cornerstone Blog
Many scientific endeavors take place quietly behind laboratory walls, but this week's In the News items are worth shouting about. A genomics expert will share his insights about CHOP's precision medicine experience at the inaugural Advances in Genome Biology and…
Published on Jul 26, 2016 in Cornerstone Blog
Nurses have a distinct worldview and approach to patient and family care that is not reflected in other specialties. Nurses are the providers who spend the most time with patients, so they are the ones who see the issues and questions that arise.
Published on Apr 26, 2016 in Cornerstone Blog
The Research Trainee Advisory Committee at The Children’s Hospital of Philadelphia Research Institute has named Hakon Hakonarson, MD, PhD, the inaugural winner of its Award for Excellence in Mentoring Research Trainees. The award recognizes faculty who effectively guide and…
Published on Apr 15, 2016 in Cornerstone Blog
This week’s stories have elements that sound like fiction, but all are real, new scientific and medical findings: A condition that turns the body’s soft tissues into bone has new hope for a future treatment. Genetic superheroes walk among us, and they may not even know it. And…
Published on Apr 8, 2016 in Cornerstone Blog
Check out the most exciting research news from The Children’s Hospital of Philadelphia this week. From leading a group of international researchers who identified a new syndrome to working on a prestigious panel that will give guidance about ways to advance treatments for…
Published on Apr 5, 2016 in Cornerstone Blog
A new issue of Bench to Bedside, the monthly newsmagazine from The Children’s Hospital of Philadelphia Research Institute, is now available! This month’s issue includes several stories that show that, sometimes, it takes some setbacks to pave a new and unexpected path to success…
Published on Mar 18, 2016 in Cornerstone Blog
Welcome to our latest weekly summary of research news from The Children’s Hospital of Philadelphia! This has been a full week, including multiple studies of genetic influences on weight in childhood, a useful autism research explainer, findings on long-term impacts of congenital…
Published on Mar 1, 2016 in Cornerstone Blog
Poster Day at The Children’s Hospital of Philadelphia Research Institute is a tradition now in its 26th year. At this event, trainee-level researchers come together to present poster summaries of their work with the CHOP community.
Published on Jan 25, 2016 in Cornerstone Blog
Research at The Children’s Hospital of Philadelphia never stops. To help keep you informed about new discoveries and CHOP researchers’ views on timely topics, we are bringing together a roundup of news highlights. Look for this as a recurring feature here on Cornerstone.
Published on Oct 1, 2015 in Cornerstone Blog
A new $3.6 million grant from the National Institutes of Health’s Electronic Medical Records and Genomics (eMERGE) program will allow scientists at The Children’s Hospital of Philadelphia to not only uncover the genetic causes of autism and other pediatric conditions, but also…
Published on Sep 1, 2015 in Cornerstone Blog
Many autoimmune diseases run in families, and because individual patients often have more than one autoimmune condition, clinicians have long suspected that these disorders have shared genetic predispositions.
Published on Jun 5, 2015 in Cornerstone Blog
CHOP Research’s Distinguished Research Trainee Awards provide institution-wide recognition for exceptional CHOP Research trainees, and offer an opportunity for mentors to highlight the work of their researchers-in-training.
Published on Mar 24, 2015 in Cornerstone Blog
A new study from The Children’s Hospital of Philadelphia shows body mass index (BMI) during infancy may help to predict childhood obesity by age four.
Published on Mar 13, 2015 in Cornerstone Blog
Researchers from the Center for Applied Genomics at The Children’s Hospital of Philadelphia investigating a serious, rare disease called common variable immunodeficiency have discovered a gene linked to immune defense.
Published on Feb 11, 2015 in Cornerstone Blog
Scientists have identified four new genes associated with the severe food allergy eosinophilic esophagitis (EoE).
Published on Feb 4, 2015 in Cornerstone Blog
The Precision Medicine Initiative, which President Obama first announced in his 2015 State of the Union speech, calls for new funding to build a national infrastructure to help sophisticated biomedical data flow from health clinics to DNA sequencing labs and back again as…
Published on Nov 26, 2014 in Cornerstone Blog
An international team of gene experts has identified a mutation that causes aplastic anemia, a serious blood disorder in which the bone marrow fails to produce normal amounts of blood cells.
Published on Oct 6, 2014 in Cornerstone Blog
A large genetic study conducted by experts at The Children’s Hospital of Philadelphia and University of Pennsylvania’s Perelman School of Medicine represents a first step in discerning the overall genetic architecture of cognitive abilities.
Published on Sep 19, 2014 in Cornerstone Blog
Researchers at The Children’s Hospital of Philadelphia are investigating why some of us seem to need more sleep than others.
Published on Jul 15, 2014 in Cornerstone Blog
In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child’s need for pain-control drugs.
Published on Jun 23, 2014 in Cornerstone Blog
New research from The Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania details how a diabetes-related gene functions on a biological pathway that affects the release of insulin.
Published on Jun 11, 2014 in Cornerstone Blog
After analyzing the DNA from thousands of patients, investigators from Children’s Hospital have uncovered several gene networks that may play important roles in autism.
Published on Apr 22, 2014 in Cornerstone Blog
In the U.S., a disease is considered rare if it affects fewer than 200,000 people. Many rare diseases have genetic origins, and almost 70 percent of Americans affected by a rare disease are children, according to the National Organization for Rare Disorders (NORD).
Published on Apr 17, 2014 in Cornerstone Blog
Two recent studies expand the list of genes associated with body fat and body mass index (BMI), and their connection to heart disease, high blood pressure, and diabetes.
Published on Mar 6, 2014 in Cornerstone Blog
The list of genes affecting blood pressure is expanding, as researchers pursue likely targets for therapeutics already in existence or in development.
Published on Jan 9, 2014 in Cornerstone Blog
A recently published book edited by The Children’s Hospital of Philadelphia’s Struan F.A. Grant, PhD, examines the role genetic variants play in causing or raising the risk of obesity.
Published on Nov 21, 2013 in Cornerstone Blog
An international team of researchers, including several investigators from The Children's Hospital of Philadelphia's Center for Applied Genomics, recently discovered a gene associated with a high risk of severe childhood asthma. The specific gene variant may be an…
Published on Sep 26, 2013 in Cornerstone Blog
A new study detailing the largest-ever genetic analysis of blood pressure in African Americans has identified five gene variants linked to the trait. According to the study, which was published recently in the American Journal of Human Genetics, three of the gene variants have…
Published on Jul 23, 2013 in Cornerstone Blog
According to the CDC, approximately 4 to 6 percent of U.S. children under the age of 18 have food allergies. Food allergies can lead to a range of symptoms, from hives to abdominal cramps to serious, life-threatening conditions like anaphylaxis.
Published on May 17, 2013 in Cornerstone Blog
The United States has a weight problem: according to the CDC, more than one-third of American adults are obese. Moreover, as of 2010 one-third of children were either overweight or obese, with the rates of obesity doubling in children and tripling in adolescents in the past…
Published on Feb 19, 2013 in Cornerstone Blog
Dr. Hakonarson, director of the Center for Applied Genomics at Children's Hospital, led the study, which is the first to look at copy variation numbers in children that may be linked with human lifespan. Several gene variants can influence a person's potential lifespan…
Published on Jan 16, 2013 in Cornerstone Blog
Genetics researchers at The Children's Hospital of Philadelphia have found 25 "high impact" gene variants that occur in some patients with autism. Although rare individually, each genetic variant has a strong effect in raising a person's autism risk. These…
Published on Dec 12, 2012 in Cornerstone Blog
The holiday season is once again upon us! While it's a time for family and friends to gather, indulge in traditions, and celebrate this season of giving, it's also hard to believe another year has passed.
Published on Dec 5, 2012 in Cornerstone Blog
Genes provide tremendous information about how our bodies work and our possible predisposition for a variety of diseases and conditions. Researchers are working to discern what specific genes and gene regions play a role in disease. The Children's Hospital of Philadelphia…