Delivering Solutions that Change Children’s Lives
Children’s Hospital of Philadelphia Research Institute is committed to discovering and developing novel breakthroughs to deliver solutions that change children’s lives. In the 2024 Research Annual Report, explore how our efforts are making a real-world impact by accelerating research for clinical integration, creating leading-edge technologies, and strengthening partnerships. We remain steadfast in our mission to nurture a world-class academic medical research community and spread our thought leadership globally, so every child has the best opportunity for a bright future.
Did you know CHOP Research Institute is home to one of the largest pediatric research programs in the country and is pushing the boundaries of medical breakthroughs? Join Executive Vice President and Chief Scientific Officer Susan Furth, MD, PhD, and several of the investigators who are working to solve the most challenging problems in children’s health in this video that highlights some of our latest amazing achievements in creating life-changing solutions for children. For optimal viewing, please use the latest version of Safari, Firefox, or Chrome.
In This Report
CHOP physicians and scientists are researching CRISPR gene editing for inherited blindness, gene therapy for genetic hearing loss, and they contributed to research supporting the first FDA-approved gene therapy treatments for sickle cell disease.
CHOP researchers are developing novel technologies and tools to make lifesaving predictions, treat patients, and advance clinical research.
Transformational gifts from foundations, donors, and industry partners are driving scientific and clinical research forward at CHOP.
The launch of new centers, programs, and buildings showcase a pioneering spirit and commitment to improving pediatric health.
CHOP researchers are making real-world impacts by creating an algorithm to track pediatric sepsis nationally, leading the development of the first pediatric neuroblastoma treatment guidelines, and more.
Learn how research participant Marie-Chantal Tornyenu’s life changed in 2021, when she enrolled in a gene therapy clinical trial for sickle cell disease at CHOP.
Where Discovery Leads
This year, we examined the new CHOP Biobank, which has the potential to drive omics-based translational research and unlock the secrets to childhood health and disease. Learn more in our feature story and video.
Ortiz-Gonzalez Lab
Get to know what life is like working in the Ortiz-Gonzalez Lab, from a diverse work culture to a focus on translational science, in this Lab Life video.
George Lab
A talented and diverse team of researchers in the George Lab work on developing novel therapeutics to treat hemophilia, including gene-based therapies. Step behind the scenes of their research in this installment of our Lab Life video series.
Timko Research Group
Driven by their close interactions with patients and families, the Timko Research Group takes an innovative approach to studying restrictive eating disorders. Learn more in their Lab Life video.