Jeffrey S Barrett, PhD, FCP

  • Department: Pediatrics
  • Division: Clinical Pharmacology
  • Email: barrettj@email.chop.edu
  • Primary Address:
    The Children's Hospital of Philadelphia
    Abramson Research Center, Room 916G
    34th & Civic Center Boulevard
    Philadelphia, PA 19104
  • (267)426-5479

    Expertise

    Dr. Barrett investigates sources of variation in pharmacokinetics and pharmacodynamics, and the development of pharmacometric approaches to advance PK/PD, novel biomarker development and disease progression modeling.

    Appointments

    Research Associate Professor of Pediatrics, University of Pennsylvania School of Medicine (2003 – present)

    Education

    PhD, Pharmacokinetics, University of Michigan (1990)
    MS, Pharmacokinetics, University of Michigan (1987)
    BS, Chemical Engineering, Drexel University (1986)

    Selected Publications

    Martin Ne, Howell S, Martin LL, Cirillo I, Barrett JS. No clinically relevant CYP 3A4 induction with the dual ACE/NEP inhibitor, M100,240. J Clin Pharmacol. Vol 44(4) . 2004:379-387.
    Pfister M, Martin NE, Haskell LP, Barrett JS. Optimizing dose selection with modeling and simulation: application to the vasopeptidase inhibtor M1002240. J Clin Pharmacol. Vol 44(6) . 2004.
    Shi J, Montay G, Chapel S, Hardy P, Barrett JS, Sack M, Marbury T, Swan S, Vargas R, Leclerc V, Leroy B, Bhargava V. Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment. J Clin Pharmacol. Vol 44(3) . 2004:234-244.
    Barrett JS, Collison KR. Dosing LMWHs in Special Populations. Thrombosis Research and Treatment: Bench to Bedside. Medical and Engineering Publishers, Inc., Washington, DC (ISBN:1-930636-03-2); 2004.