As part of The Center for Cellular and Molecular Therapeutics, the Research Vector Core (RVC) has expanded its capacity to provide infrastructure support for investigators interested in using viral vectors in their research model systems.

RVC utilizes molecular biology techniques to engineer and produce recombinant AAV vectors for gene transfer in research experiments or non-clinical studies. RVC staff work closely with investigators to plan and develop vectors for individual project requirements. The RVC has extensive experience in the production of multiple AAV serotypes. Due to its unique manufacturing method, resulting in high productivity, the RVC is able to deliver empty capsid free (<1%) vectors after the purification process. Reporter gene vectors are available directly from inventory.

The core is under the direction of Dr. Shangzhen Zhou, a leading expert in AAV vector production. The core employs a team of dedicated technicians to provide research vectors with premium quality.

For any further information, please contact Junwei Sun at sunj@email.chop.edu

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