Presentations
May 15-16, 2006 HIV Preclinical - Clinical Therapeutics Research Meeting, Bethesda , MD
- Neurokinin-1R (SP Receptor) Antagonists for HIV Therapy
Steven D. Douglas
November 16, 2005 Dinner Meeting
- Introduction: Neurokinin-1R (SP Receptor) Antagonists for HIV Therapy
Steven D. Douglas - Establishing simian NK cell parameters for the study of NK-1R antagonists in vivo
Jordon Orange- Steve D.Douglas - Neurokinin-1 Receptor Antagonist (Aprepitant) Inhibits Drug-Resistant HIV-1 Infection of Monocyte-Derived Macrophages in vitro
Xu Wang, Steven D. Douglas, Jian-Ping Lai, Pablo Tebas, Janet L. Lathey, Wen-Zhe Ho - IPCP Core C Activities: Aprepitant Dose-exposure Relationship in the Monkey
Jeffrey Barrett
August 4, 2005 Site Visit
- Substance P Receptor (Neurokinin-1R) Antagonists as Therapeutic Agents in HIV
Steven D. Douglas - "Neurokinin-1 Receptor Antagonist (Aprepitant) Inhibits Drug-Resistant HIV-1 Infection of Monocyte-Derived Macrophages in vitro"
Xu Wang - "Expression of Different Isoforms of Neurokinin-1 Receptor (NK-1R) During Monocyte-Macrophage Differentiation and Functional Implications"
JP Lai - Project 1: Anti-HIV Mechanisms of NK-1R Antagonists
PI -Wen-Zhe Ho; Co-I - Steven D. Douglas - Project 2: Cellular Mechanisms and Interaction of Neurokinin-1 Receptor (NK-1R) Antagonists and HIV Co-Receptors CCR5 and CXCR4
(PI -Steven D. Douglas; Co-I - L.E. Kilpatrick, J.P. Lai) - Project 3: SIV Models of Neurobehavioral, Antiviral, and Immunomodulatory SP Antagonist(s) Effects
Andrew A. Lackner, Kate Baker - Project 4: Human Studies of Neurokinin-1 Receptor Antagonists in HIV-1
PI: Pablo Tebas; Co-PI: Jeffrey Barrett, Dwight Evans, David Dinges, Jordan Orange, Ruben Gur - Core A: Administrative Core
PI: Steve D. Douglas - Core B: SeraCare BioServices Research Laboratories
Janet L Lathey - Core C: Biostatistics and Pharmacology Core
Avital Cnaan, Jeffrey Barrett