- Active clinical trials: 88
- Study coordinators within
the CTO: 35
- Coordinators certified by the Association of Clinical Research Professionals: 18
- Enrollment goals met on studies conducted in the CTO: 85%
The Clinical Trials Office (CTO) at The Children's Hospital of Philadelphia is a centralized office that provides resources and assistance to clinical research investigators, enabling them to carry out clinical research in a manner consistent with the Hospital's goals – excellent patient care, top-quality education, and innovative research. The CTO has expertise in implementing, conducting, and monitoring clinical trials and provides a variety of services that benefit both novice and experienced clinical researchers. The CTO is designed to ensure the excellence and compliance of an investigator's clinical research trial.
The Children's Hospital of Philadelphia established the CTO in 1999 as part of the institution's emphasis on clinical research. Since then, the CTO has experienced rapid growth.
The CTO advances the quality and quantity of clinical research at Children's Hospital and its associated network. Specifically, the CTO supports research at the Hospital by developing and completing submissions to the Hospital's Institutional Review Board; assisting in the preparation of Investigational New Drug and Investigational Device exemption application submissions to the Federal Drug Administration; conducting clinical research studies under the guidance of principal investigators; and developing budgets and providing research training for investigators, study coordinators, and administrative staff.
The CTO staff works in partnership with investigators to ensure the protection of human subjects in accordance with Good Clinical Practice, federal, state and/or local regulations and the requirements of the study sponsor.