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Center for Applied Genomics

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CAG Study Finds Variants Behind Childhood Obesity Risk

Two gene variants appear to play a critical role in the development of common childhood obesity.

  • Read a report from USA Today
  • Read a review in the Philadelphia Inquirer
  • Read the abstract at Nature Genetics

CAG Chip Pinpoints New Target to Prevent Heart Disease

Cardiochip, a gene analysis tool designed by CAG’s Brendan Keating, links the IL6R gene with coronary heart disease.

  • Read a report from Forbes
  • Read a review at the CHOP Pressroom
  • Read the full article at The Lancet

Largest-Ever Gene Study of Type 2 Diabetes Finds Variants

CAG co-leads an international consortium uncovering genes that may point to biological targets for developing more effective Type 2 Diabetes treatments

  • Review the DSN press report
  • Read the PubMed abstract

CAG Study Points to Brain Signaling Defects in ADHD

At least 10% of patients affected by same subgroup of mutations

  • Review the release at CHOP Press
  • Check out a review at Medline Plus
  • Read the abstract at Nature Genetics

CAG and BGI Announce New Genome Partnership!

Joint Genome Center to Conduct Large-Scale Sequencing

  • Press Release from the CHOP Press Room
  • YouTube interviews with CAG Director Hakon Hakonarson and BGI's Wayne Wei Liu
  • Online review at Forbes Magazine

Recent News

  • WORK FOR US!
  • Hamamy Syndrome Cause Discovered
  • Population Explosion Means More Rare Variants
  • Breaking the Genome Bottleneck

Our Team

Our Team

Our aim is to discover the genetic causes of prevalent childhood diseases and translate findings into medical innovations.

For Participants

For Participants

The Center is engaged in a number of major research projects, and we aim to collect and analyze data from more than 100,000 children.

For Researchers

For Researchers

We collaborate with researchers in the academic, public, and private sectors. The Center has the capacity to genotype thousands of samples per week.

Disease Studies

Disease Studies

We currently have more than 50 active disease projects - internally and in collaboration with research teams in North America, Europe, and Asia.

Neurodevelopment Study

Neurodevelopment Study

With the University of Pennsylvania, we have undertaken a major project to explore key components of brain development.

CAG Media

CAG in the Media

CAG regularly features in national and international media. Watch videos and read reviews of our most prominent research.

Fun Stuff

Fun Stuff

We have compiled a small catalog of learning resources. See our lab in action, take a tour of the brain, or browse links to our favorite resources.

Support CAG

Support CAG

CAG is discovering new and better ways to diagnose and treat childhood disorders. Your support can help launch innovative research projects.

Internal

Internal

For CAG staff only. Please use your CHOP username and password to log in.

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Our Supporters

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