The Children's Hospital of Philadelphia 34th Street and Civic Center Boulevard

Cystic Fibrosis
Lung transplantation

Federal Meaningful Use Program

Epithelial ion transport
Cystic Fibrosis

Assistant Professor of Pediatrics at University of Pennsylvania School of Medicine (2007– present)
MD, Mount Sinai School of Medicine (1998)
BA, Biology, Johns Hopkins University (1994)
Selected Publications
Kreindler James L, Chen Bei, Kreitman Yael, Kofonow Jennifer, Adams Kelly M, Cohen Noam A. The novel dry extract BNO 1011 stimulates chloride transport and ciliary beat frequency in human respiratory epithelial cultures.. American journal of rhinology & allergy. Vol 26(6) . 2012 Nov-Dec:439-43.
Lee Robert J, Xiong Guoxiang, Kofonow Jennifer M, Chen Bei, Lysenko Anna, Jiang Peihua, Abraham Valsamma, Doghramji Laurel, Adappa Nithin D, Palmer James N, Kennedy David W, Beauchamp Gary K, Doulias Paschalis-Thomas, Ischiropoulos Harry, Kreindler James L, Reed Danielle R, Cohen Noam A. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection.. The Journal of clinical investigation. Vol 122(11) . 2012 Nov:4145-59.
Kreindler James L. Is the best offense a good D-fense? Should we use vitamin D as adjunctive therapy for asthma?. American journal of respiratory and critical care medicine. Vol 186(6) . 2012 Sep:470-2.
Zhao Ke-Qing, Cowan Andrew T, Lee Robert J, Goldstein Natalia, Droguett Karla, Chen Bei, Zheng Chunquan, Villalon Manuel, Palmer James N, Kreindler James L, Cohen Noam A. Molecular modulation of airway epithelial ciliary response to sneezing.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Vol 26(8) . 2012 Aug:3178-87.
Zhao Ke-Qing, Xiong Guoxiang, Wilber Morgan, Cohen Noam A, Kreindler James L. A role for two-pore K+ channels in modulating Na+ absorption and Cl- secretion in normal human bronchial epithelial cells.. American journal of physiology. Lung cellular and molecular physiology. Vol 302(1) . 2011 Sep:L4-L12.
Cheng Guanjun, Wang Liang-Chuan S, Fridlender Zvi G, Cheng Guang-Shing, Chen Bei, Mangalmurti Nilam S, Saloura Vassiliki, Yu Zaifang, Kapoor Veena, Mozdzanowska Krystyna, Moon Edmund, Sun Jing, Kreindler James L, Cohen Noam A, Caton Andrew J, Erikson Jan, Albelda Steven M. Pharmacologic activation of the innate immune system to prevent respiratory viral infections.. American journal of respiratory cell and molecular biology. Vol 45(3) . 2011 Sep:480-8.
Zhao Ke-Qing, Goldstein Natalia, Yang Haibin, Cowan Andrew T, Chen Bei, Zheng Chunquan, Palmer James N, Kreindler James L, Cohen Noam A. Inherent differences in nasal and tracheal ciliary function in response to Pseudomonas aeruginosa challenge.. American journal of rhinology & allergy. Vol 25(4) . 2011 Jul-Aug:209-13.
Suaud Laurence, Miller Katelyn, Alvey Lora, Yan Wusheng, Robay Amal, Kebler Catherine, Kreindler James L, Guttentag Susan, Hubbard Michael J, Rubenstein Ronald C. ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.. The Journal of biological chemistry. Vol 286(24) . 2011 Jun:21239-53.
Accurso Frank J, Moss Richard B, Wilmott Robert W, Anbar Ran D, Schaberg Amy E, Durham Todd A, Ramsey Bonnie W,. Denufosol tetrasodium in patients with cystic fibrosis and normal to mildly impaired lung function.. American journal of respiratory and critical care medicine. Vol 183(5) . 2011 Mar:627-34.
Chen Kong, Pociask Derek A, McAleer Jeremy P, Chan Yvonne R, Alcorn John F, Kreindler James L, Keyser Matthew R, Shapiro Steven D, Houghton A McGarry, Kolls Jay K, Zheng Mingquan. IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke.. PloS one. Vol 6(5) . 2011:e20333.