George
 
H.
 
Rothblat
Ph.D.
Email: 
rothblat@email.chop.edu
Address: 
The Children?s Hospital of Philadelphia Abramson Building, Room 1102C 3615 Civic Center Blvd.
215-590-0585
Affiliations
Expertise
Appointments
Research Professor of Pediatrics at University of Pennsylvania School of Medicine (2000 – 2013)
Education
Ph.D., Medical Microbiology, University of Pennsylvania (1961)
B.S., Bacteriology, University of Connecticut (1957)
Selected Publications
Yancey PG, Bortnick AE, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Rothblat GH.. Importance of different pathways of cellular cholesterol efflux.. Arterioscler Thromb Vasc Biol. Vol 1:23(5) . 2003:712-719.
Asztalos BF, de la Llera-Moya M, Dallal GE, Horvath KV, Schaefer EJ, Rothblat GH.. Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux.. J Lipid Res. Vol 46((10)) . 2005 Oct:2246-2253.
Zhang Y, Da Silva JR, Reilly M, Billheimer JT, Rothblat GH, Rader DJ.. Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo.. J Clin Invest. Vol 115(10) . 2005 Oct:2870-2874.
Zimetti F, Weibel GK, Duong M, Rothblat GH.. Measurement of cholesterol bidirectional flux between cells and lipoproteins.. J Lipid Res. Vol 47(3) . 2006 Mar:605-613.
Duong, PT, Collins, HL, Nickel, M, Lund-Katz, S, Rothblat, GH, Phillips, MC. Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I. J Lipid Res. Vol 47. 2006 Apr:832-843.
Duong M-N, Collins HL, Jin W, Zanotti I, Favari E, Rothblat GH. Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages.. Arterioscler Thromb Vasc Biol. Vol 26(3) . 2006 Mar:541-547.
Adorni MP, Zimetti F, Billheimer JT, Wang N, Rader, DJ, Phillips MC, Rothblat GH. The roles of different pathways in the release of cholesterol from macrophages. J Lipid Res. Vol 48. 2007:2453-2462.
Duong PT, Lund-Katz S, Rothblat GH, Phillips MC. Comparison of the cellular lipid efflux properties of pre-beta high-density lipoprotein and lipid-free apolipoprotein A-I. Arterioscler Thromb Vasc Biol. Vol 27. 2007:150.
Weibel GL, Alexander ET, Joshi MR, Rader DJ, Lund-Katz S, Phillips MC, Rothblat GH. A comparative study of cellular lipid mobilizaition and efflux to human apoA-I and apoA-I Milano. Arterioscler Throm and Vasc Biol. Vol 27(9) . 2007 Sep 27:2022-2029.
Sankaranarayanan S, Oram JF, Asztalos BF, Vaughan AM, Lund-Katz S, Adorni MP, Phillips MC, Rothblat GH. Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux. J Lipid Res. Vol 50(2) . 2009 Feb:275-284.