Edward
 
F.
 
Attiyeh
M.D.
Email: 
Attiyeh@email.chop.edu
Address: 
Children's Hospital of Philadelphia 3501 Civic Center Blvd., CTRB 3050
(267) 426-5534
Affiliations
Affiliations
Affinity Groups:
Genes,Genomics and Pediatric Disease
Centers of Emphasis:
Childhood Cancer Research
Expertise
Appointments
Assistant Professor of Pediatrics at University of Pennsylvania School of Medicine (2007– present)
Education
M.D., Albert Einstein College of Medicine (1999)
A.B., Molecular Biology, Princeton University (1995)
Selected Publications
Pugh Trevor J, Morozova Olena, Attiyeh Edward F, Asgharzadeh Shahab, Wei Jun S, Auclair Daniel, Carter Scott L, Cibulskis Kristian, Hanna Megan, Kiezun Adam, Kim Jaegil, Lawrence Michael S, Lichenstein Lee, McKenna Aaron, Pedamallu Chandra Sekhar, Ramos Alex H, Shefler Erica, Sivachenko Andrey, Sougnez Carrie, Stewart Chip, Ally Adrian, Birol Inanc, Chiu Readman, Corbett Richard D, Hirst Martin, Jackman Shaun D, Kamoh Baljit, Khodabakshi Alireza Hadj, Krzywinski Martin, Lo Allan, Moore Richard A, Mungall Karen L, Qian Jenny, Tam Angela, Thiessen Nina, Zhao Yongjun, Cole Kristina A, Diamond Maura, Diskin Sharon J, Mosse Yael P, Wood Andrew C, Ji Lingyun, Sposto Richard, Badgett Thomas, London Wendy B, Moyer Yvonne, Gastier-Foster Julie M, Smith Malcolm A, Auvil Jaime M Guidry, Gerhard Daniela S, Hogarty Michael D, Jones Steven J M, Lander Eric S, Gabriel Stacey B, Getz Gad, Seeger Robert C, Khan Javed, Marra Marco A, Meyerson Matthew, Maris John M. The genetic landscape of high-risk neuroblastoma.. Nature genetics. Vol 45(3) . 2013 Mar:279-84.
Chand Damini, Yamazaki Yasuo, Ruuth Kristina, Schönherr Christina, Martinsson Tommy, Kogner Per, Attiyeh Edward F, Maris John, Morozova Olena, Marra Marco A, Ohira Miki, Nakagawara Akira, Sandström Per-Erik, Palmer Ruth H, Hallberg Bengt. Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma.. Disease models & mechanisms. Vol 6(2) . 2013 Mar:373-82.
Diskin Sharon J, Capasso Mario, Schnepp Robert W, Cole Kristina A, Attiyeh Edward F, Hou Cuiping, Diamond Maura, Carpenter Erica L, Winter Cynthia, Lee Hanna, Jagannathan Jayanti, Latorre Valeria, Iolascon Achille, Hakonarson Hakon, Devoto Marcella, Maris John M. Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.. Nature genetics. 2012 Sep.
Schleiermacher G, Mosseri V, London W B, Maris J M, Brodeur G M, Attiyeh E, Haber M, Khan J, Nakagawara A, Speleman F, Noguera R, Tonini G P, Fischer M, Ambros I, Monclair T, Matthay K K, Ambros P, Cohn S L, Pearson A D J. Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project.. British journal of cancer. 2012 Sep.
Bosse Kristopher R, Diskin Sharon J, Cole Kristina A, Wood Andrew C, Schnepp Robert W, Norris Geoffrey, Nguyen Le B, Jagannathan Jayanti, Laquaglia Michael, Winter Cynthia, Diamond Maura, Hou Cuiping, Attiyeh Edward F, Mosse Yael P, Pineros Vanessa, Dizin Eva, Zhang Yongqiang, Asgharzadeh Shahab, Seeger Robert C, Capasso Mario, Pawel Bruce R, Devoto Marcella, Hakonarson Hakon, Rappaport Eric F, Irminger-Finger Irmgard, Maris John M. Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity.. Cancer research. Vol 72(8) . 2012 Apr:2068-78.
Gumy-Pause Fabienne, Pardo Bruno, Khoshbeen-Boudal Mary, Ansari Marc, Gayet-Ageron Angèle, Sappino André-Pascal, Attiyeh Edward F, Ozsahin Hulya. GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma.. Genes, chromosomes & cancer. Vol 51(2) . 2012 Feb:174-85.
Dondeti Vijay R, Wubbenhorst Bradley, Lal Priti, Gordan John D, D'Andrea Kurt, Attiyeh Edward F, Simon M Celeste, Nathanson Katherine L. Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets.. Cancer research. Vol 72(1) . 2012 Jan:112-21.
Dubois Steven G, Geier Ethan, Batra Vandana, Yee Sook Wah, Neuhaus John, Segal Mark, Martinez Daniel, Pawel Bruce, Yanik Greg, Naranjo Arlene, London Wendy B, Kreissman Susan, Baker David, Attiyeh Edward, Hogarty Michael D, Maris John M, Giacomini Kathleen, Matthay Katherine K. Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group.. International journal of molecular imaging. Vol 2012. 2012:250834.
Nguy?n L? B, Diskin Sharon J, Capasso Mario, Wang Kai, Diamond Maura A, Glessner Joseph, Kim Cecilia, Attiyeh Edward F, Mosse Yael P, Cole Kristina, Iolascon Achille, Devoto Marcella, Hakonarson Hakon, Li Hongzhe K, Maris John M. Phenotype Restricted Genome-Wide Association Study Using a Gene-Centric Approach Identifies Three Low-Risk Neuroblastoma Susceptibility Loci.. PLoS genetics. Vol 7(3) . 2011 Mar:e1002026.
Cole Kristina A, Huggins Jonathan, Laquaglia Michael, Hulderman Chase E, Russell Mike R, Bosse Kristopher, Diskin Sharon J, Attiyeh Edward F, Sennett Rachel, Norris Geoffrey, Laudenslager Marci, Wood Andrew C, Mayes Patrick A, Jagannathan Jayanti, Winter Cynthia, Mosse Yael P, Maris John M. RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma.. Proceedings of the National Academy of Sciences of the United States of America. Vol 108(8) . 2011 Feb:3336-41.