March 2013

"Now in the United States, we don’t see many deaths in the first three years, which is a real triumph for newborn screening and the care that follows."- Kwaku Ohene-Frempong, MD

Improving Sickle Cell Disease Care in the U.S. and Abroad

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According to the CDC, sickle cell disease (SCD), a group of inherited blood disorders, affects between 90,000 and 100,000 Americans, most of them African American or Black. SCD is characterized by episodes of pain, chronic anemia, and other complications. While SCD may only affect a small percentage of Americans, millions more worldwide live with the effects of SCD every day. While discussing his  …

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Children with Heart Defects May Experience Abnormal Growth Regulation

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The poor growth seen in children born with complex heart defects may result from factors beyond deficient nutrition, and a new study suggests that abnormalities in overall growth regulation could play a role. “When compared with their healthy peers, children with congenital heart disease have impaired growth, as measured in weight, length, and head circumference,” said the study’s senior author Me …

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Using Next-Generation Sequencing to Understand and Treat Disease

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How time flies: it seems almost impossible that the many events of 2003 are now almost ten years in the past. It’s also hard to believe that the completion of the Human Genome Project, a government-led initiative involving researchers from all around the world, was nearly a decade ago. In addition, the way next-generation sequencing technology has developed in the past decade is almost unbelievabl …

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Latest Issue of Discovery to Innovation Now Online

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The most recent issue of Discovery to Innovation is now available online. The issue features research revealing factors that contribute to disease, findings that may one day lead to new therapies, funding that will make continued investigations possible, and much more.

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Vaccine Expert Paul Offit, M.D., Honored Twice

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The Children’s Hospital of Philadelphia’s Paul A. Offit, M.D., was recently lauded for his more than three decades of vaccine research and advocacy with back-to-back honors from two separate organizations. In February the blog Vaccine Nation named Dr. Offit one of the 50 most influential people in vaccines, and just recently he was awarded the 2013 Maxwell Finland Award for Scientific Achievement, …

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Say Hello to Research in Action

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We are excited to welcome another member of The Children’s Hospital of Philadelphia family to the blogosphere: the Center for Injury Research and Prevention has launched a new blog! Research in Action features news and commentary on the important work being done at the Center for Injury Research and Prevention every day, and will tackle such topics as teen driving, child safety seats, and concussi …

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Barth Syndrome Foundation Announces Funding Opportunities

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The Barth Syndrome Foundation (BSF) invites researchers to submit proposals for the organization’s Research Grant Program. The BSF offers funding for basic clinical and scientific research on the biochemical basis, natural history, and treatment of Barth syndrome. Since 2002, the BSF has awarded over $2.7 million to investigators studying this condition. Barth syndrome (BTHS) is a rare, x-linked g …

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Researcher’s Innovative Immune Therapy Featured on The Doctors

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The innovative work being done by The Children’s Hospital of Philadelphia’s Stephen Grupp, M.D., was recently featured on the CBS TV show The Doctors. Dr. Grupp, the Center for Childhood Cancer Research’s director of translational research, discussed his trial using immune therapy treat an aggressive form of childhood leukemia, acute lymphoblastic leukemia (ALL). While roughly 85 percent of ALL ca …

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U.S. News & World Report Names CHOP Pediatrics #1

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Great news! The Children’s Hospital of Philadelphia has been named the top pediatrics graduate program in the country! U.S. News & World Report recently released its 2014 Best Graduate Schools rankings, and Children’s Hospital, along with its academic affiliate, the University of Pennsylvania’s Perelman School of Medicine, garnered the #1 spot in Pediatrics. The Perelman School of Medicine’s D …

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Congratulations to Our 2013 CHOP Research Poster Day Award Winners!

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The Children’s Hospital of Philadelphia Research Institute celebrated its 23rd Annual CHOP Research Poster Day on February 27, 2013, with over 160 cutting-edge research posters on display in the Colket Translational Research Building. This event recognizes the outstanding research conducted at CHOP each year, and honors our exceptional trainee participants. This year, 40 individuals were selected  …

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Clinical and Translational Research Center Offering New Services

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Comprising ten core facilities, the Clinical and Translational Research Center (CTRC) provides the resources, environment, operations, and training to support and promote the highest quality clinical and translational research by qualified investigators. The CTRC is pleased to announce that an Ophthalmology Core (OC) has been established to provide clinical and translational research services in o …

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Impact of Sequestration

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As you are likely aware, in accordance with the Budget Control Act of 2011, a series of spending cuts, called sequestration, will cancel approximately $85 billion in budgetary resources across the Federal government for the remainder of the Federal fiscal year. It is possible that existing awards may be affected, including the cancelation of continuation awards, or negotiating a reduction in the s …

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