February 2014

“Bringing these new types of vaccines into clinical use will take years of work, but this study represents an important first step along the way.”- Philip R. Johnson, MD

CHOP Research Leader Contributes to Novel Virus Study

Novel_Virus_Study

The Children’s Hospital of Philadelphia Research Institute’s chief scientific officer, Philip R. Johnson, MD, is among the co-authors of a new study that presents an advanced approach to vaccine design. This innovation, in which artificial proteins are custom-designed as vaccine components, offers the promise of a new way to prevent serious childhood infections caused by respiratory syncytial viru …

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Geography Affects Kidney Transplant Waiting Period

Kidney_Transplant

A new study from researchers at The Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania has revealed large geographic variation in waiting times for children across the United States in need of kidney transplants, with differences due mainly to local supply and demand. The findings, which appeared in the Journal of the American Society of Nephr …

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Genetic Investigation Explores Heart Disease Risk

Heart_Disease_Risk

New research from The Children’s Hospital of Philadelphia and the University of Pennsylvania strengthens the case that one well-known type of cholesterol — low-density lipoprotein, or LDL — is a likely suspect in causing heart disease, but also casts doubt on the role played by another type, triglycerides. The findings may guide the search for improved treatments for heart disease. Most of us have …

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Pediatrics Study Finds Tonsillectomy Care Quality Variation

Tonsillectomy_Care

A recent study of perioperative tonsillectomy care that involved several researchers from The Children’s Hospital of Philadelphia found “substantial variation” in the quality of tonsillectomy care across children’s hospitals in the U.S. The study, which was recently published in Pediatrics, was led by Sanjay Mahant, MD, MSc, FRCPC, of Toronto’s Hospital for Sick Children. Children’s Hospital’s Ron …

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Research Advocates Dispirited Over NIH Funding

NIH_Funding

Biomedical research advocates had hoped that a surge in research and development funding in the 2014 budget would be the best medicine for the National Institutes of Health, which has been impaired by mandated across-the-board sequestration cuts. Instead, the $1 billion increase slated for NIH in the $1.1 trillion appropriations bill passed by Congress in January was a bitter pill. While the boost …

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Collaborations Set to Advance Children’s Healthcare

Advance_Childrens_Healthcare

Along with its research partners Drexel University and Hebrew University of Jerusalem, The Children’s Hospital of Philadelphia Research Institute recently hosted a collaborative research symposium that gave researchers from all three institutions the chance to connect and share ideas. The Advancing Healthcare for Children symposium, held Jan. 27-29, brought together investigators for presentations …

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Examining Neurodevelopment Following TTTS Surgery

TTTS_Surgery

The Center for Fetal Diagnosis and Treatment at CHOP serves more than 150 families with complicated multiples pregnancies each year and performs more than 50 fetoscopic laser surgeries annually, one of the highest volumes of prenatal laser surgeries in the nation. A multiyear study at CHOP looked at the neurocognitive effects of twin-twin transfusion syndrome (TTTS) in monochorionic twins who unde …

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Neurologist Receives “Taking Flight” Epilepsy Award

Epilepsy_Award

The Children’s Hospital of Philadelphia’s Ethan Goldberg, MD, PhD, recently received an award from the epilepsy advocacy organization Citizens United for Research in Epilepsy (CURE) to study using transplanted cells to treat epilepsy. Dr. Goldberg was one of three researchers to receive a “Taking Flight” award, a one-year grant of up to $100,000 designed to “promote the careers of young investigat …

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CRISSP Alumna Finds Future Career Path Through Internship

CRISSP

The Children’s Hospital of Philadelphia’s Research Institute is dedicated to training undergraduates by giving them hands-on exposure to sophisticated scientific and research techniques. The CHOP Research Institute Summer Scholars Program (CRISSP) provides full-time mentored research experience to future leaders in the biomedical sciences, with a special emphasis on advancing laboratory, clinical, …

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Key Alex’s Lemonade Stand Grant to Bridge Funding Gap

Alexs_Lemonade_Stand

A new Springboard Grant awarded by Alex’s Lemonade Stand Foundation will jumpstart a CHOP childhood cancer research project that fell short of funding due to sequester cuts within the National Institutes of Health. Hematologist Stella T. Chou, MD, will receive $100,000 over the course of one year to fund her research on how an extra chromosome 21 and mutations in a transcription factor gene called …

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New Director to Build on Center’s Success

New_Director

As the new director of CHOP’s Center for Pediatric Clinical Effectiveness (CPCE), Theoklis Zaoutis, MD, MSCE, will do what he enjoys most — create, develop, and build new ideas. Dr. Zaoutis co-founded the CPCE, a Center of Emphasis within the Children’s Hospital of Philadelphia Research Institute. It provides infrastructure for training in and performance of clinical effectiveness research, which  …

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CHOP Researcher Sets Goals as New ISTSS President

ISTSS_President

Reaching out across the globe to advance traumatic stress research and practice is a top goal that CHOP’s Nancy Kassam-Adams, PhD, plans to accomplish as the new president of the International Society for Traumatic Stress Studies (ISTSS). Traumatic stress occurs in significant numbers of children and parents after unintentional injuries such as concussions, interpersonal violence, and other diffic …

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