April 2013

“This study describes how these cells have a potent anticancer effect in children.”- Stephan A. Grupp, MD, PhD

Advanced Cell Therapy Eliminates Aggressive Leukemia in Two Children


According to new research from The Children’s Hospital of Philadelphia and the University of Pennsylvania, two children with an aggressive form of childhood leukemia achieved a complete response after being treated with an innovative cell therapy. In the study, both patients’ immune systems were reprogrammed to rapidly multiply and destroy leukemia cells. The study appears in the April 18 issue of …

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National Teen Driving Report Finds Safety Gains for Teen Passengers


A new report on teen driver safety by The Children’s Hospital of Philadelphia and State Farm® shows encouraging trends among teen passengers. In 2011 more than half of teen passengers (54 percent) reported “always” buckling up, and from 2008 to 2011, risky behaviors of teen passengers (ages 15 to 19 years) declined: the number of teen passengers killed in crashes not wearing seat belts decreased 2 …

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ASCI Honors Four CHOP Physician-Scientists


Four junior investigators from the Children’s Hospital of Philadelphia’s Department of Pediatrics have been chosen to receive the prestigious 2013 Young Physician-Scientist Award by the American Society for Clinical Investigation (ASCI). The ASCI, established in 1908 and one of the nation’s oldest and most respected honor societies, recognizes physician-scientists with superb records of scholarly  …

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President Obama Unveils Ambitious Brain-Mapping Initiative


Almost exactly ten years after the successful completion of the Human Genome Project, President Obama recently unveiled another large, government-backed research project: the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) initiative. Calling the brain “an enormous mystery waiting to be unlocked,” President Obama laid out broad plans for the project, which will devote more th …

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CHOP’s John Maris, M.D., Set to Lead Pediatric Cancer “Dream Team”


John M. Maris, M.D., director of The Children’s Hospital of Philadelphia’s Center for Childhood Cancer Research has been chosen to lead the first- ever pediatric “Dream Team” solely focused on creating new treatments for the most challenging childhood cancers. Stand Up to Cancer (SU2C) and the St. Baldrick’s Foundation, along with the American Association for Cancer Research (AACR), SU2C’s scienti …

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2013 CHOP Mentor Award Winners Announced


The Office of Faculty Development recently announced the recipients of the 2013 Children’s Hospital Mentor Award. The 2013 Chop Mentor Award winners are Mary Catherine Harris, M.D., Ron Keren, M.D., M.P.H., and Mitchell J. Weiss, M.D., Ph.D. The annual CHOP Mentor Award is given to up to three faculty members who have “demonstrated extraordinary dedication to fostering the professional development …

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CHOP Teams Up With Pfizer to Speed Pediatric Research and Development


he Children’s Hospital of Philadelphia and Pfizer, Inc., are joining forces with the goal of translating biomedical discoveries into novel treatments. Children’s Hospital is set join the Centers for Therapeutic Innovation (CTI) network, a novel collaboration model built by Pfizer that brings academic researchers together with Pfizer scientists to expedite the pace of innovation. Children’s Hospita …

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40 Distinguished Years: Celebrating the Career of Beverly J. Lange, M.D.


As part of a celebration of her career, Beverly J. Lange, M.D., who recently retired after 40 years of pioneering research and leadership, delivered the third Anna T. Meadows lecture. In her talk, “Survival on the Yellow Brick Road,” Dr. Lange discussed her work with chemotherapy-related cognitive dysfunction while also highlighting some of the accomplishments of her time at The Children’s Hospita …

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Genetic Study Suggests Fine-Tuning Drugs for Pediatric Brain Tumors Regulation


Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child’s tumor. “By better understanding the basic bi …

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2013 CHOP Distinguished Research Trainee Awards Announced


The CHOP Research Institute has announced the winners of the 2013 CHOP Distinguished Research Trainee Awards, which provide institution- wide recognition for exceptional CHOP Research trainees, and create an avenue for mentors to show appreciation for their researchers-in-training. The Office of Postdoctoral Affairs sought nominations for the award from faculty mentors in three trainee categories: …

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CHOP Ranked Top NIH-Funded Children’s Hospital


We’re pleased to announce that during the 2012 Federal fiscal year, The Children’s Hospital of Philadelphia Research Institute received more NIH funding than any other independent children’s hospital. Children’s Hospital received more than $125 million in NIH funds in 2012, beating out Boston Children’s Hospital. This good news is the latest in a series of #1 rankings and honors. In its recent lis …

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Tom Curran, Ph.D., F.R.S., Joins Fellows of the AACR Academy


A world-renowned cancer investigator at The Children’s Hospital of Philadelphia was recently honored by the American Association for Cancer Research as it inaugurated the first class of the Fellows of the AACR Academy. Tom Curran, Ph.D., F.R.S., deputy scientific director of The Children’s Hospital of Philadelphia Research Institute, was formally inducted into the Academy on April 5 in Washington, …

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2013 CHOP Research Institute Scientific Symposium to Promote Collaboration, Emphasize Discovery


On May 2 and 3, 2013, The Children’s Hospital of Philadelphia Research Institute will celebrate another year of scientific innovation and discovery at its annual Scientific Symposium. This event, taking place in the Colket Translational Research Building, will showcase the groundbreaking work of some of CHOP’s most successful researchers. Since its inception in 2004, the CHOP Research Institute Sc …

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Announcing the 2013 QED Application Cycle


Since 2009, the QED Proof-of-Concept Program operated by the University City Science Center has supported life science technology development at universities across the Greater Philadelphia Region. Established in 1963 and headquartered in Philadelphia, PA, the Science Center runs QED within a suite of commercialization programs to help researchers turn their ideas into realities. In partnership wi …

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