“CHOP is at the forefront of teen driver safety research, and it is an amazing place to take these leaps because of our interdisciplinary nature.”

- Flaura Koplin Winston, MD, PhD

Breakthrough Work Leads to Rare Bone Disease Trial

As rare pediatric diseases go, Fibrodysplasia Ossificans Progressiva (FOP) is about as rare and debilitating as rare diseases come. Affecting approximately one in two million people around the world,  …

Mutation Helps Explain How Our Body Clock is Set

Most of us have failed to get enough sleep on a few occasions. Maybe it was as a college student studying for final exams, or as a new parent consoling an infant who is teething. Remember how you drag …

Investigators Take Clinical Look at Teen Driver Safety

Crashes remain the leading cause of young adult death (ages 16 to 24) with four times the number of deaths from cancer and 38 times the number of deaths from the flu. In fact, a teen’s highest lifetim …

Discovering, Optimizing Epilepsy Therapies with Genetics

A new study led by The Children’s Hospital of Philadelphia’s David Bearden, MD, and Ethan M. Goldberg, MD, PhD, supports the idea that the identification of specific genetic targets could lead to a se …

Intervention Aims to Promote Effective Practice for ADHD

Approximately 7,800 children with attention-deficit/hyperactivity disorder (ADHD) visit primary care practices across The Children’s Hospital of Philadelphia Care Network. Treating such a large patien …

Healthy Weight Program Launches Study on Microbiome

Trillions of naturally occurring bacteria and other microbes coexist in the human gut and are part of how we process food and harness energy. Known as the microbiome, this complex collection’s potenti …

Report Supports Prenatal Spina Bifida Surgery as Standard of Care

Reporting on 100 recent cases of fetal surgery for spina bifida, specialists from The Children’s Hospital of Philadelphia achieved results similar to those in a landmark clinical trial that establishe …

Researchers Discover Gene Mutation in Blood Disorder

An international team of scientists has identified a gene mutation that causes aplastic anemia, a serious blood disorder in which the bone marrow fails to produce normal amounts of blood cells. Studyi …

Genetic Study Gives Clues to Intellectual Abilities

As students with bulging backpacks return to school this fall, each one also brings a unique skill set to the classroom. One child may be a math whiz, while their buddy in the next desk is an avid rea …

Gene-regulating Protein Reaches Multiple Disease Pathways

Genomic scientists at The Children’s Hospital of Philadelphia recently found strong evidence that the protein family FOXA2 is a master regulator of genetically vulnerable pathways in multiple diseases …

Scholar Hope Grant Supports Neuroblastoma Research

Pediatric oncology researchers at The Children’s Hospital of Philadelphia are driven to find new treatments for childhood cancer, and the Hyundai Hope On Wheels program is supporting their hard work b …

Research Institute Leader Named to Brain Tumor Foundation Panel

The Children’s Hospital of Philadelphia Research Institute’s Tom Curran, PhD, FRS, was recently named to a panel of experts who will advise the Pediatric Brain Tumor Foundation (PBTF). A pediatric bra …