A recent genomic study of neuroblastoma reinforces the challenges of treating the most aggressive forms of this disease. Contrary to expectations, the researchers found relatively few recurrent gene mutations — mutations that would suggest new targets for neuroblastoma treatment. Instead, the investigators have refocused on how neuroblastoma tumors evolve in response to medicine and other factors.
Tag Archive: Neuroblastoma
Permanent link to this article: http://www.research.chop.edu/blog/study-shows-neuroblastoma-evolves-rapidly-limiting-treatment-targets/
Dec 06 2012
For decades, researchers at The Children’s Hospital of Philadelphia have worked to better understand and treat neuroblastoma, a cancer of nerve tissue.Neuroblastoma is frequently aggressive, causing approximately 12 percent of all childhood cancer deaths. In high-risk forms of the disease, the cancer tends to return after initial treatment, often with deadly results. Using powerful gene-analysis …
Permanent link to this article: http://www.research.chop.edu/blog/chop-researchers-identify-two-gene-mutations-linked-to-neuroblastoma/