Tag Archive: chromatin looping

Jan 14 2014

Flipping a Gene Switch Reactivates Fetal Hemoglobin, May Reverse Sickle Cell Disease

Hematologists have long sought to reactivate fetal hemoglobin as a treatment for children and adults with sickle cell disease (SCD). Researchers at CHOP have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period.

Permanent link to this article: http://www.research.chop.edu/blog/flipping-gene-switch-reactivates-fetal-hemoglobin-may-reverse-sickle-cell-disease/