Category Archive: The Children’s Hospital of Philadelphia
What one researcher describes as asthma, another might call reactive airway disease. Unfortunately, such examples demonstrate the lack of a common pediatric research terminology, which presents a barrier to data reuse, sharing, and integration.
Permanent link to this article: http://www.research.chop.edu/blog/researchers-must-talk-talk-advance-science/
A study led by a CHOP neonatology expert showed that infants with severe retinopathy of prematurity (ROP) diagnosed and treated under modern protocols remain at risk of nonvisual disabilities, even if blindness can be averted in most children.
Permanent link to this article: http://www.research.chop.edu/blog/severe-retinopathy-prematurity-associated-functional-disability/
For medical devices, as with many medicines, the market for children is a small fraction of the adult market, and there are far fewer child-sized devices. But the need for pediatric medical devices exists, even if proper devices may not.
Permanent link to this article: http://www.research.chop.edu/blog/chop-drexel-consortium-boost-pediatric-medical-device-pipeline/
Three studies under way at The Children’s Hospital of Philadelphia are looking at potential ways to desensitize children so that they can develop a level of tolerance to peanut protein that would provide some clinical protection against accidental exposure.
Permanent link to this article: http://www.research.chop.edu/blog/three-peanut-immunotherapy-studies-way/
The use of prophylactic antibiotics to prevent urinary tract infections associated with vesicoureteral reflux has been controversial, and a multisite clinical trial that The Children’s Hospital of Philadelphia participated in is adding to the debate.
Permanent link to this article: http://www.research.chop.edu/blog/prophylactic-antibiotics-cut-rate-repeat-utis-half/
An organelle found in all eukaryotic cells, the endoplasmic recticulum (ER) plays an important role in the manufacture and delivery of enzymes, lipids, and proteins.
Permanent link to this article: http://www.research.chop.edu/blog/molecular-cell-paper-explores-endoplasmic-reticulum-stress-response/
As part of its commitment to training the next generation of pediatric pioneers, every year CHOP Research takes time to honor its exceptional trainees, and recently announced the 2014 Distinguished Research Trainee Award winners.
Permanent link to this article: http://www.research.chop.edu/blog/illustrating-commitment-education-chop-research-honors-trainees/
In the U.S., a disease is considered rare if it affects fewer than 200,000 people. Many rare diseases have genetic origins, and almost 70 percent of Americans affected by a rare disease are children, according to the National Organization for Rare Disorders (NORD).
Permanent link to this article: http://www.research.chop.edu/blog/rare-disease-project-makes-progress-empowers/
At birth, infants move from a sterile environment to one full of microorganisms. They rapidly acquire alterations in their immune systems that help them to survive in this dirty world.
Permanent link to this article: http://www.research.chop.edu/blog/going-gut-build-preterm-infants-immunity/
Traditionally, genetic counselors interview parents and hand-draw pedigrees, but they now have a new app to create those diagrams digitally on an iPad® screen with a few finger taps.
Permanent link to this article: http://www.research.chop.edu/blog/new-ipad-app-helps-construct-genetic-pedigrees/