Category Archive: The Children’s Hospital of Philadelphia
CHOP has long investigated biodegradable nanoparticles for medical use. With diameters ranging from a few tens to a few hundreds of nanometers, these particles are 10 to 1000 times smaller than red blood cells.
Permanent link to this article: http://www.research.chop.edu/blog/biodegradable-nanoparticles-may-hold-therapeutic-use/
Two dedicated “dream teams” of investigators will shape innovative solutions to address unmet pediatric medical needs, as part of a research partnership with The Children’s Hospital of Philadelphia, Drexel University, and The Hebrew University of Jerusalem.
Permanent link to this article: http://www.research.chop.edu/blog/unique-collaboration-leads-dream-teams-advance-pediatric-research/
A study at The Children’s Hospital of Philadelphia aims to establish reference data for children ages 1 to 5 using dual-energy X-ray absorptiometry (DXA), a test that measures bone density.
Permanent link to this article: http://www.research.chop.edu/blog/early-childhood-bone-density-reference-data-needed/
What one researcher describes as asthma, another might call reactive airway disease. Unfortunately, such examples demonstrate the lack of a common pediatric research terminology, which presents a barrier to data reuse, sharing, and integration.
Permanent link to this article: http://www.research.chop.edu/blog/researchers-must-talk-talk-advance-science/
A study led by a CHOP neonatology expert showed that infants with severe retinopathy of prematurity (ROP) diagnosed and treated under modern protocols remain at risk of nonvisual disabilities, even if blindness can be averted in most children.
Permanent link to this article: http://www.research.chop.edu/blog/severe-retinopathy-prematurity-associated-functional-disability/
For medical devices, as with many medicines, the market for children is a small fraction of the adult market, and there are far fewer child-sized devices. But the need for pediatric medical devices exists, even if proper devices may not.
Permanent link to this article: http://www.research.chop.edu/blog/chop-drexel-consortium-boost-pediatric-medical-device-pipeline/
Three studies under way at The Children’s Hospital of Philadelphia are looking at potential ways to desensitize children so that they can develop a level of tolerance to peanut protein that would provide some clinical protection against accidental exposure.
Permanent link to this article: http://www.research.chop.edu/blog/three-peanut-immunotherapy-studies-way/
The use of prophylactic antibiotics to prevent urinary tract infections associated with vesicoureteral reflux has been controversial, and a multisite clinical trial that The Children’s Hospital of Philadelphia participated in is adding to the debate.
Permanent link to this article: http://www.research.chop.edu/blog/prophylactic-antibiotics-cut-rate-repeat-utis-half/
An organelle found in all eukaryotic cells, the endoplasmic recticulum (ER) plays an important role in the manufacture and delivery of enzymes, lipids, and proteins.
Permanent link to this article: http://www.research.chop.edu/blog/molecular-cell-paper-explores-endoplasmic-reticulum-stress-response/
As part of its commitment to training the next generation of pediatric pioneers, every year CHOP Research takes time to honor its exceptional trainees, and recently announced the 2014 Distinguished Research Trainee Award winners.
Permanent link to this article: http://www.research.chop.edu/blog/illustrating-commitment-education-chop-research-honors-trainees/