Category Archive: Center for Applied Genomics
Researchers at The Children’s Hospital of Philadelphia are investigating why some of us seem to need more sleep than others.
Permanent link to this article: http://www.research.chop.edu/blog/gene-mutation-helps-explain-body-clock-set/
In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child’s need for pain-control drugs.
Permanent link to this article: http://www.research.chop.edu/blog/chop-researchers-discover-postsurgical-pain-gene-variants/
After analyzing the DNA from thousands of patients, investigators from Children’s Hospital have uncovered several gene networks that may play important roles in autism.
Permanent link to this article: http://www.research.chop.edu/blog/autism-gene-networks-offer-treatment-targets/
In the U.S., a disease is considered rare if it affects fewer than 200,000 people. Many rare diseases have genetic origins, and almost 70 percent of Americans affected by a rare disease are children, according to the National Organization for Rare Disorders (NORD).
Permanent link to this article: http://www.research.chop.edu/blog/rare-disease-project-makes-progress-empowers/
Two recent studies expand the list of genes associated with body fat and body mass index (BMI), and their connection to heart disease, high blood pressure, and diabetes.
Permanent link to this article: http://www.research.chop.edu/blog/studies-find-genes-linked-bmi-cardiovascular-health/
The list of genes affecting blood pressure is expanding, as researchers pursue likely targets for therapeutics already in existence or in development.
Permanent link to this article: http://www.research.chop.edu/blog/new-gene-signals-likely-blood-pressure-drug-targets/
A recently published book edited by The Children’s Hospital of Philadelphia’s Struan F.A. Grant, PhD, examines the role genetic variants play in causing or raising the risk of obesity.
Permanent link to this article: http://www.research.chop.edu/blog/chop-genetics-expert-edits-book-examining-genetics-obesity/
An international team of researchers, including several investigators from The Children’s Hospital of Philadelphia’s Center for Applied Genomics, recently discovered a gene associated with a high risk of severe childhood asthma.
Permanent link to this article: http://www.research.chop.edu/blog/international-team-discovers-childhood-asthma-gene/
A new study detailing the largest-ever genetic analysis of blood pressure in African Americans has identified five gene variants linked to the trait.
Permanent link to this article: http://www.research.chop.edu/blog/african-american-blood-pressure-study-identifies-new-gene-variants/
A team from the Perelman School of Medicine at the University of Pennsylvania recently published a study in Nature Medicine that sheds light on food allergy-associated inflammation.
Permanent link to this article: http://www.research.chop.edu/blog/penn-team-finds-immune-cells-promote-food-allergy-associated-inflammation/