Transforming Discoveries Into Solutions
Children’s Hospital of Philadelphia Research Institute discovers, develops, and delivers solutions that change children’s lives. In the 2023 Research Annual Report, learn how our work has a tangible impact as we accelerate research for clinical integration, create leading-edge technologies, and strengthen partnerships. Our unwavering commitment is to cultivate a world-class academic medical research community and spread our thought leadership worldwide to help children everywhere thrive.
Did you know CHOP Research Institute has been contributing to medical breakthroughs for more than 100 years? Join Executive Vice President and Chief Scientific Officer Susan Furth, MD, PhD, and four of our top scientists in this video that highlights a few of our latest amazing achievements and successes in creating life-changing solutions for children.
In This Report
CHOP clinical research laid the groundwork for U.S. Food and Drug Administration approvals of life-changing treatments, including three new therapies for rare diseases.
CHOP researchers and clinicians are developing novel technologies to make lifesaving predictions, treat patients, and advance clinical research.
Funding from generous donors is propelling scientific and clinical research at CHOP.
A commitment to innovation and inclusivity radiates with the launch of new programs, buildings, and centers.
CHOP is making a global impact with its research, contributing to new international concussion recommendations, standardizing neonatal resuscitation guidelines, and more.
Read one research participant’s story and the path to approval for the first drug to treat Friedreich’s ataxia, a rare neurodegenerative disorder.
Where Discovery Leads
This year, we took an in-depth look at our scientific research aimed at addressing gun violence and prevention. Learn more in feature stories and videos.
Song Laboratory
Meet the Song Lab team in their Lab Life video. Utilizing molecular targets identified in mechanistic studies, the Song Lab aims develop novel therapeutic strategies for patients with neural injury, stroke, and neurodegenerative diseases.
Vanderver Laboratory
Meet the Vanderver team in their Lab Life video. Discoveries in the Vanderver Lab have led to meaningful advances in how we approach and treat leukodystrophies and other white matter disorders.
Spinner Laboratory
In this Lab Life video, Dr. Spinner and Melissa Gilbert, PhD, Manager of the Translational Research Division of Genomic Diagnostics, share the background and context of the lab's research into the genetic underpinnings of pediatric developmental disease as well as the clinical impact of their work.
Peranteau Laboratory
Go behind the scenes of the Peranteau Lab and learn what drives the team's innovative and impactful research into fetal interventions, in this Lab Life video.
Mir Laboratory
By developing and applying advanced microscopy technologies, researchers in the Mir Lab are exploring limitless avenues of discovery when it comes to improving our understanding of gene regulation during embryonic development and beyond. See the Mir Lab evolve both physically and conceptually in this Lab Life video.